Oral health care knowledge among Phenylketonuria patients in the Latvian population

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dc.contributor.authorĀbola, Iveta
dc.contributor.authorIntlere, Nikola Anna
dc.contributor.authorBrinkmane, Anda
dc.contributor.authorLaktina, Sabine
dc.contributor.authorZariņa, Agnese
dc.contributor.authorVasilevska, Lauma
dc.contributor.authorSkadiņš, Ingus
dc.contributor.authorMoisejevs, Georgijs
dc.contributor.authorGailīte, Linda
dc.contributor.authorAuzenbaha, Madara
dc.contributor.institutionDepartment of Conservative Dentistry and Oral Health
dc.contributor.institutionScientific Laboratory of Molecular Genetics
dc.contributor.institutionDepartment of Biology and Microbiology
dc.date.accessioned2024-12-05T07:10:02Z
dc.date.available2024-12-05T07:10:02Z
dc.date.issued2024-12
dc.descriptionPublisher Copyright: © 2024 The Authors
dc.description.abstractBACKGROUND: Phenylketonuria (PKU) is an autosomal recessive inherited disorder of phenylalanine (Phe) metabolism that results from a deficiency of phenylalanine hydroxylase (PAH). Patients with PKU rely on amino acid mixtures and low-protein diets, which often exhibit an acidic nature and pose various challenges to oral health. The objective of the study was to evaluate oral care habits of PKU patients in Latvia and the impact of the recommendations developed on improving oral care. MATERIALS AND METHODS: In this study, during a one-month interval before and after the implementation of oral hygiene recommendations, questionnaires were distributed to all patients with PKU diagnosed in Latvia, with a response rate of 78 % (79 of 101). RESULTS: The group older and 18 years of age showed a poorer understanding of oral care even after receiving recommendations, 82 % brushing their teeth twice a day (92 % in the group <18 years of age), continuing 57 % rinsing their mouth after using amino acid formula (75 % in the younger group). Significant improvements were observed only in the respondent group younger than 18 years of age - including increases in toothbrushing twice a day by 25 % ( p = 0.001), dental flossing by 23 % ( p = 0.001), mouth rinsing after amino acid-based formula by 13 % ( p = 0.020). CONCLUSION: This study concludes that PKU patients older and 18 years of age have a poor understanding of maintaining oral hygiene and the use of the necessary supplements to improve it. Activities are needed in the future that would regularly remind and motivate PKU patients to take care of their oral health.en
dc.description.statusPeer reviewed
dc.format.extent6
dc.format.extent585295
dc.identifier.citationĀbola, I, Intlere, N A, Brinkmane, A, Laktina, S, Zariņa, A, Vasilevska, L, Skadiņš, I, Moisejevs, G, Gailīte, L & Auzenbaha, M 2024, 'Oral health care knowledge among Phenylketonuria patients in the Latvian population', Molecular Genetics and Metabolism Reports, vol. 41, 101167. https://doi.org/10.1016/j.ymgmr.2024.101167
dc.identifier.doi10.1016/j.ymgmr.2024.101167
dc.identifier.issn2214-4269
dc.identifier.otherMendeley: 2437b62c-c214-3cec-9b37-53b75cbb6e2f
dc.identifier.otherunpaywall: 10.1016/j.ymgmr.2024.101167
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/16950
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85210095447&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMolecular Genetics and Metabolism Reports
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDental health education
dc.subjectDental status
dc.subjectOral health
dc.subjectPhenylketonuria
dc.subject3.3 Health sciences
dc.subject1.6 Biological sciences
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectMolecular Biology
dc.subjectGenetics
dc.subjectEndocrinology
dc.titleOral health care knowledge among Phenylketonuria patients in the Latvian populationen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview

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