Focused open necrosectomy in necrotizing pancreatitis

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dc.contributor.authorPupelis, Guntars
dc.contributor.authorFokin, Vladimir
dc.contributor.authorZeiza, Kaspars
dc.contributor.authorPlaudis, Haralds
dc.contributor.authorSuhova, Anastasija
dc.contributor.authorDrozdova, Nadezda
dc.contributor.authorBoka, Viesturs
dc.date.accessioned2021-08-02T13:35:01Z
dc.date.available2021-08-02T13:35:01Z
dc.date.issued2013
dc.description.abstractBackground: The control of sepsis is the primary goal of surgical intervention in patients with infected necrosis. Simple surgical approaches that are easy to reproduce may improve outcomes when specialists in endoscopy are not available. The aim of the present study was to describe the experience with abs focused open necrosectomy (FON) in patients with infected necrosis. Method: A prospective pilot study conducted to compare a semi-open/closed drainage laparotomy and FON with the assistance of peri-operative ultrasound. The incidence of sepsis, dynamics of C-reactive protein (CRP), intensive care unit (ICU)/hospital stay, complication rate and mortality were compared and analysed. Results: From a total of 58 patients, 36 patients underwent a conventional open necrosectomy and 22 patients underwent FON. The latter method resulted in a faster resolution of sepsis and a significant decrease in mean CRP on Day 3 after FON, P = 0.001. Post-operative bleeding was in 1 versus 7 patients and the incidence of intestinal and pancreatic fistula was 2 versus 8 patients when comparing FON to the conventional approach. The median ICU stay was 11.6 versus 23 days and the hospital stay was significantly shorter, 57 versus 72 days, P = 0.024 when comparing FON versus the conventional group. One patient died in the FON group and seven patients died in the laparotomy group, P = 0.139. Discussion: FON can be an alternative method to conventional open necrosectomy in patients with infected necrosis and unresolved sepsis.en
dc.description.statusPeer reviewed
dc.format.extent6
dc.format.extent89121
dc.identifier.citationPupelis, G, Fokin, V, Zeiza, K, Plaudis, H, Suhova, A, Drozdova, N & Boka, V 2013, 'Focused open necrosectomy in necrotizing pancreatitis', HPB, vol. 15, no. 7, pp. 535-540. https://doi.org/10.1111/hpb.12004
dc.identifier.doi10.1111/hpb.12004
dc.identifier.issn1365-182X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/5933
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=84892660211&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofHPB
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectHepatology
dc.subjectGastroenterology
dc.titleFocused open necrosectomy in necrotizing pancreatitisen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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