Uztura-DNS testu izpēte, salīdzināšana un to zinātniskā pamatojuma izvērtēšana.
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Date
2021
Authors
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Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Pašlaik DTC-GT uzņēmumu skaits, kas piedāvā ģenētiskās testēšanas pakalpojumus bez speciālistu iesaistīšanas, pieaug. Šī tendence ir tiešas sekas ievērojamam genotipēšanas un sekvencēšanas izmaksu samazinājumam. DTC-GT uzņēmumi piedāvā prognozes sarežģītu slimību attīstības riskiem dzīves laikā un piedāvā ieteikumus personīgajam dzīvesveidam. Lielāka daļa šādu uzņēmumu piedāvā uztura DNS testus. Šie uzņēmumi veido uztura ieteikumus specifisku slimību profilaksei, balstoties uz cilvēka personīgo ģenētisko izcelsmi.
Uztura ieteikumus nosaka, pamatojoties uz ierobežotu ģenētisko marķieru kopumu. Darbā tika analizēti DTC-GT pakalpojumi, ko piedāvā 30 uzņēmumi visā pasaulē, lai iegūtu vispārēju priekšstatu par piedāvāto pakalpojumu zinātniskās precizitātes līmeni. Turklāt darba ietvaros tika veikta viena gadījuma izpēte, lai salīdzinātu ieteikumus par uzturu un personalizētās diētas, kas tiek piedāvātas vienam indivīdam. Veiktā analīze uzskatāmi parāda vajadzību pēc īpašām vadlīnijām, kā arī pēc zinošu speciālistu iesaistīšanas, lai nodrošinātu uztura DNS testu pareizu interpretāciju.
Currently, the number of DTC-GT (direct-to-consumer genetic-testing) companies, offering genetic testing services without the involvement of specialists, are growing. This development is a direct consequence of the significant decrease in genotyping and sequencing costs. DTC-GT companies offer predictions about the risk of developing complex diseases during the life. As a result, they offer suggestions for personal lifestyle. A lot of companies provide nutrition DNA tests. These companies suggest dietary indications, as a main solution in the prevention of specific diseases, based on one’s personal genetic background. Dietary patterns are defined on the basis of a limited set of genetic markers. We analyse the DTC-GT nutrigenetics services offered by 30 companies worldwide, to obtain an overall picture of the types of nutritional traits considered and the level of scientific precision of the DNA tests that are proposed. Furthermore, we have organized a one case research, in order to compare the personalized diets that have been proposed for one individual. Our analysis expressly states the need for specific guidelines and involvement of knowledgeable specialists, in order to ensure the right interpretation of nutrition DNA tests.
Currently, the number of DTC-GT (direct-to-consumer genetic-testing) companies, offering genetic testing services without the involvement of specialists, are growing. This development is a direct consequence of the significant decrease in genotyping and sequencing costs. DTC-GT companies offer predictions about the risk of developing complex diseases during the life. As a result, they offer suggestions for personal lifestyle. A lot of companies provide nutrition DNA tests. These companies suggest dietary indications, as a main solution in the prevention of specific diseases, based on one’s personal genetic background. Dietary patterns are defined on the basis of a limited set of genetic markers. We analyse the DTC-GT nutrigenetics services offered by 30 companies worldwide, to obtain an overall picture of the types of nutritional traits considered and the level of scientific precision of the DNA tests that are proposed. Furthermore, we have organized a one case research, in order to compare the personalized diets that have been proposed for one individual. Our analysis expressly states the need for specific guidelines and involvement of knowledgeable specialists, in order to ensure the right interpretation of nutrition DNA tests.
Description
Uzturzinātne
Nutrition Science
Veselības aprūpe
Health Care
Nutrition Science
Veselības aprūpe
Health Care
Keywords
Uztura DNS testi, DTC_GT, uztura ģenētika, uztura genomika., DNA nutrition test, DTC-GT – direct-to-consumer genetic-testing, nutrigenetics, nutrigenomics.