DEPRESSION AND OXIDATIVE STRESS INTERACTION IN STABLE CORONARY HEART DISEASE

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dc.contributor.authorIvaščenko, Tarass
dc.contributor.authorVoicehovskis, Vladimirs V.
dc.contributor.authorKalējs, Oskars
dc.contributor.authorVoicehovska, Jūlija G.
dc.contributor.authorŠķesters, Andrejs
dc.contributor.authorPahomova, Natālija
dc.contributor.authorLejnieks, Aivars
dc.contributor.institutionDepartment of Internal Diseases
dc.contributor.institutionBioķīmijas zinātniskā laboratorija
dc.date.accessioned2022-11-24T12:40:02Z
dc.date.available2022-11-24T12:40:02Z
dc.date.issued2022
dc.descriptionPublisher Copyright: © Latvian Academy of Sciences.
dc.description.abstractIt was concluded that depression (D) is an independent risk factor for cardiovascular diseases (CVD), and is not related to other previously determined cardiac risk factors. Compared with non-depressed patients, the risk of cardiac arrest increased in less severely depressed patients. D worsens the CVD prognosis by significantly increasing the risk of recurrent coronary heart disease (CHD). Some studies suggest that OS directly increases the risk of D in patients with CVD. Oxidative stress (OS) is considered an emergency mechanism that relates to both CVD and D pathophysiology. The common risk factors increase the production of OS and reduce antioxidant defences, thereby promoting the occurrence and development of interacted ischaemic CVD and D. At present, there is insufficient evidence that routine screening of D in patients with CHD will ultimately help improve the patient's condition. This review reiterates the need for a multidisciplinary approach, which is necessary to understand, diagnose and then treat this frequent co-morbid condition of CHD and D. Assessment of OS markers could modify risk stratification, diagnosis and prevention and treatment of patients with both CHD and D, in patients with and without previous cardiac history.en
dc.description.statusPeer reviewed
dc.format.extent7
dc.format.extent501985
dc.identifier.citationIvaščenko, T, Voicehovskis, V V, Kalējs, O, Voicehovska, J G, Šķesters, A, Pahomova, N & Lejnieks, A 2022, 'DEPRESSION AND OXIDATIVE STRESS INTERACTION IN STABLE CORONARY HEART DISEASE', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 76, no. 2, pp. 181-187. https://doi.org/10.2478/prolas-2022-0028
dc.identifier.doi10.2478/prolas-2022-0028
dc.identifier.issn1407-009X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/9801
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85141090525&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectglutatione peroxidase
dc.subjectmalondialdehyde
dc.subjectmental health disorders
dc.subjectreactive oxygen species
dc.subjectstable coronary heart disease
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral
dc.subjectSDG 3 - Good Health and Well-being
dc.titleDEPRESSION AND OXIDATIVE STRESS INTERACTION IN STABLE CORONARY HEART DISEASEen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview

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