Systematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiology

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dc.contributor.authorEstévez-López, Fernando
dc.contributor.authorMudie, Kathleen
dc.contributor.authorWang-Steverding, Xia
dc.contributor.authorBakken, Inger Johanne
dc.contributor.authorIvanovs, Andrejs
dc.contributor.authorCastro-Marrero, Jesús
dc.contributor.authorNacul, Luis
dc.contributor.authorAlegre, Jose
dc.contributor.authorZalewski, Paweł
dc.contributor.authorSłomko, Joanna
dc.contributor.authorStrand, Elin Bolle
dc.contributor.authorPheby, Derek
dc.contributor.authorShikova, Evelina
dc.contributor.authorLorusso, Lorenzo
dc.contributor.authorCapelli, Enrica
dc.contributor.authorSekulic, Slobodan
dc.contributor.authorScheibenbogen, Carmen
dc.contributor.authorSepulveda, Nuno
dc.contributor.authorMurovska, Modra
dc.contributor.authorLacerda, Eliana
dc.contributor.authoron behalf of The European Network on ME/CFS (EUROMENE)
dc.date.accessioned2022-01-18T14:12:45Z
dc.date.available2022-01-18T14:12:45Z
dc.date.issued2020-05-21
dc.description.abstractThis review aimed at determining the prevalence and incidence of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome (ME/CFS) in Europe. We conducted a primary search in Scopus, PubMed and Web of Science for publications between 1994 and 15 June 2019 (PROSPERO: CRD42017078688). Additionally, we performed a backward-(reference lists) and forward-(citations) search of the works included in this review. Grey literature was addressed by contacting all members of the European Network on ME/CFS (EUROMENE). Independent reviewers searched, screened and selected studies, extracted data and evaluated the methodological and reporting quality. For prevalence, two studies in adults and one study in adolescents were included. Prevalence ranged from 0.1% to 2.2%. Two studies also included incidence estimates. In conclusion, studies on the prevalence and incidence of ME/CFS in Europe were scarce. Our findings point to the pressing need for well-designed and statistically powered epidemiological studies. To overcome the shortcomings of the current state-of-the-art, EUROMENE recommends that future research is better conducted in the community, reviewing the clinical history of potential cases, obtaining additional objective information (when needed) and using adequate ME/CFS case definitions; namely, the Centers for Disease Control & Prevention−1994, Canadian Consensus Criteria, or Institute of Medicine criteria.en_US
dc.identifier.doihttps://doi.org/10.3390/jcm9051557
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/7223
dc.language.isoenen_US
dc.relation.ispartofJournal of Clinical Medicine, 9(5), [1557]en_US
dc.rightsinfo:eu-repo/semantics/openAccessen_US
dc.subjectcentral nervous system diseasesen_US
dc.subjectinfections;en_US
dc.subjectmuscular diseasesen_US
dc.subjectpost-exertional malaiseen_US
dc.subjectvirus diseasesen_US
dc.titleSystematic Review of the Epidemiological Burden of Myalgic Encephalomyelitis/Chronic Fatigue Syndrome Across Europe: Current Evidence and EUROMENE Research Recommendations for Epidemiologyen_US
dc.typeArticleen_US

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