The Effect of MI Varnish™ on Caries Increment and Dietary Habits among 6- and 12-Year-Old Children in Riga, Latvia : A 3-Year Randomized Controlled Trial

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dc.contributor.authorGudkina, Jekaterīna
dc.contributor.authorAmaechi, Bennett T.
dc.contributor.authorAbrams, Stephen H.
dc.contributor.authorBrinkmane, Anda
dc.contributor.authorPetrošina, Eva
dc.contributor.institutionDepartment of Conservative Dentistry and Oral Health
dc.contributor.institutionStatistics Unit
dc.date.accessioned2022-08-16T21:03:33Z
dc.date.available2022-08-16T21:03:33Z
dc.date.issued2022-06-01
dc.descriptionFunding Information: Recruitment was facilitated by exempting volunteers from the two-year wait time required for their regular, complete (including radiographic examination) dental check-up financially supported by the government. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
dc.description.abstractAims: This randomized controlled trial investigated the effect of MI Varnish™ (5% NaF/ CPP-ACP) on caries increment in 6- and 12-year-old children in Riga, Latvia within 36 months. Methods: Forty-eight 6-year-old children (Group 1) and forty-seven 12-year-old children (Group 3) received quarterly varnish application, while forty-eight 6-year-old children (Group 2) and thirty-seven 12-yearold children (Group 4) did not have varnish applied. All children/parents received the same preventive advice. All children were visually examined using ICDAS-II criteria. Questionnaires on dietary habits were completed by the children/parents at baseline and after 36 months. DMFS and dfs were calculated from ICDAS data. The statistical analysis was performed (α = 0.05) using a Chi-squared test, paired t-test (Welch test) and the Pearson correlation coefficient. The trial registration number is ISRCTN10584414. Results: In Group 1 versus Group 2, the DMFS(SD) (Baseline/36 months) values were 5.02(5.85)/13.21(6.67) (p < 0.001) versus 2.65(4.54)/10.81(6.14) (p < 0.001), respectively; the dfs(SD) (Baseline/36 months) values were 36.75(12.96)/24.04(12.9) (p < 0.001) versus 33.67(12.74)/23.88(11.91) (p < 0.001), respectively. In Group 3 versus Group 4, the DMFS(SD) (Baseline/36 months) values were 48.62(23.18)/70.96(23.28) (p < 0.001) versus 34.73(17.99)/54.95(16.09) (p < 0.001), respectively; the dfs(SD) (Baseline/36 months) values were 1.7(4.4)/0 (p < 0.05) versus 2(6.39)/0 (p = 0.06), respectively. The prevalence of caries (dfs + DMFS) decreased by 4.52 (p < 0.001) and 1.63 (p < 0.001) in Groups 1 and 2, respectively, but increased by 20.64 (p < 0.001) and 18.22 (p < 0.001) in Groups 3 and 4, respectively. An analysis of the questionnaires indicated the habitual, frequent consumption of a sugary diet by all the children. A significant correlation (r = 0.321; p < 0.05) was observed between caries increment and the frequency of daily intake of sugary snacks, soft drinks and tea with sugar at baseline only in Group 1. Conclusions: A quarterly application of MI varnish (CPP-ACP/fluoride) reduced caries increment in 6- and 12-year-old children in Riga, Latvia.en
dc.description.statusPeer reviewed
dc.format.extent16
dc.format.extent2132016
dc.identifier.citationGudkina, J, Amaechi, B T, Abrams, S H, Brinkmane, A & Petrošina, E 2022, 'The Effect of MI Varnish™ on Caries Increment and Dietary Habits among 6- and 12-Year-Old Children in Riga, Latvia : A 3-Year Randomized Controlled Trial', Dentistry Journal, vol. 10, no. 6, 96, pp. 1-16. https://doi.org/10.3390/dj10060096
dc.identifier.doi10.3390/dj10060096
dc.identifier.issn2304-6767
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/9435
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85131800846&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofDentistry Journal
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectfluoride varnish
dc.subjectcaries increment
dc.subjectdietary habits
dc.subjectcaries prevalence
dc.subjectoral hygiene
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleThe Effect of MI Varnish™ on Caries Increment and Dietary Habits among 6- and 12-Year-Old Children in Riga, Latvia : A 3-Year Randomized Controlled Trialen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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