VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION

Abstract

The reference intervals and median values of serum vitamin B12 level in blood from patients among the Latvian population were established for different age groups with a two-year step using data for a large number of patients, accumulated in E. Gulbis Laboratory in Latvia. The data represents the general population of Latvia. An indirect in silico method, developed in E. Gulbis laboratory for determination of serum vitamin B12 blood level reference intervals, was used. Strong elevation of serum vitamin B12 blood level was observed in children who were between 2 and 10 years old. The paper discusses the serum vitamin B12 values for children and a different serum vitamin B12 reference interval for young children is suggested.

Description

Publisher Copyright: © The Authors This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

Keywords

B12 vitamin, children, general population, in silico analysis, large patient data, Latvia, reference interval, 3.1 Basic medicine, 3.3 Health sciences, 1.1. Scientific article indexed in Web of Science and/or Scopus database, General

Citation

Gavars, D, Perminov, D, Tauckels, E, Lindenberga, I, Miķelsone, A & Auce, A 2024, 'VARIATION OF SERUM VITAMIN B12 LEVEL IN THE BLOOD FROM PATIENTS OF DIFFERENT AGE AMONG THE LATVIAN POPULATION', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 78, no. 2, pp. 133-140. https://doi.org/10.2478/prolas-2024-0020