Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020

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dc.contributor.authorKauliņš, Ričards
dc.contributor.authorRudzītis, Ainārs
dc.contributor.authorLejnieks, Aivars
dc.contributor.authorKigitoviča, Dana
dc.contributor.authorSkride, Andris
dc.contributor.institutionDepartment of Internal Diseases
dc.date.accessioned2023-08-10T09:05:01Z
dc.date.available2023-08-10T09:05:01Z
dc.date.issued2023-08-06
dc.descriptionFunding Information: This research was funded by the Fundamental and Applied Research Project “Introduction of balloon pulmonary angioplasty method and evaluation of its effectiveness in the treatment of patients with chronic thromboembolic pulmonary hypertension at Pauls Stradiņš Clinical University Hospital”, grant number lzp-2020/1-0055. Publisher Copyright: © 2023 by the authors.
dc.description.abstractBackground: Chronic thromboembolic pulmonary hypertension (CTEPH) is a rare and progressive condition; however, the true characteristics of CTEPH are still unknown, as notable regional variations exist in terms of patients’ age, baseline hemodynamic data, and management choices. This report aims to investigate the baseline clinical characteristics, incidence, and risk factors associated with CTEPH patients in Latvia from 2019 to 2020. Methods: The data were analyzed from a prospective, nationwide, Latvian pulmonary hypertension registry for incident CTEPH cases. The patients’ clinical characteristics were assessed at the time of diagnosis. Results: During the course of this study, a cohort of 13 patients with CTEPH were included for analysis. Among the enrolled CTEPH patients, most exhibited low exercise and functional capacity, with a median (±IQR) 6 min walk distance of 300.0 (±150.0) m. The median values (±IQR) for mean pulmonary artery pressure and pulmonary vascular resistance were 40.0 ± 13.0 mmHg and 7.35 ± 2.82 Wood units, respectively. The most common risk factors for CTEPH were a history of acute pulmonary embolism and a blood group other than O. Conclusions: The findings of this report revealed the characteristics of the Latvian CTEPH population, indicating that a significant proportion of patients are elderly individuals with multiple comorbidities.en
dc.description.statusPeer reviewed
dc.format.extent302001
dc.identifier.citationKauliņš, R, Rudzītis, A, Lejnieks, A, Kigitoviča, D & Skride, A 2023, 'Baseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020', Medicina (Kaunas), vol. 59, no. 8, 1426. https://doi.org/10.3390/medicina59081426
dc.identifier.doi10.3390/medicina59081426
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/14614
dc.identifier.urlhttps://www.mdpi.com/1648-9144/59/8/1426
dc.identifier.urlhttps://www-webofscience-com.db.rsu.lv/wos/alldb/full-record/MEDLINE:37629717
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85168730786&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina (Kaunas)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectLatvia
dc.subjectchronic thromboembolic pulmonary hypertension
dc.subjectepidemiology
dc.subjectincidence
dc.subjectnational registry
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral Medicine
dc.titleBaseline Clinical Characteristics and Incidence of Chronic Thromboembolic Pulmonary Hypertension Patients in Latvia, 2019–2020en
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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