Circulating Levels of IL-8 and MCP-1 in Healthy Adults : Changes after an Acute Aerobic Exercise and Association with Body Composition and Energy Metabolism

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dc.contributor.authorLagzdiņa, Rudīte
dc.contributor.authorRumaka, Maija
dc.contributor.authorGersone, Gita
dc.contributor.authorTretjakovs, Pēteris
dc.contributor.institutionDepartment of Human Physiology and Biochemistry
dc.date.accessioned2024-01-26T13:20:02Z
dc.date.available2024-01-26T13:20:02Z
dc.date.issued2023-10
dc.descriptionPublisher Copyright: © 2023 by the authors.
dc.description.abstractThe most recent WHO recommendations about physical activity emphasise the importance of total exercise volume above the significance of the duration of each bout. This study examined whether acute aerobic exercise changes circulating levels of IL-8 and MCP-1 and if these changes are associated with body composition and energy metabolism. Healthy adult volunteers completed a 10 min walking–running exercise on a treadmill. Indirect calorimetry was used to determine their resting metabolic rate (RMR) and energy expenditure (EE) during the exercise. Pre-exercise levels of IL-8 and MCP-1 were similar in both sexes. There were positive correlations of pre-exercise IL-8 with body mass, waist circumference, and lean body mass in men and pre-exercise MCP-1 with RMR in women. The exercise led to an increase in IL-8 of 68% and a decrease in MCP-1 of 74% of participants. An increase in post-exercise IL-8 in men was associated with greater walking EE and a greater increase in walking EE. The increase in post-exercise MCP-1 was associated with a lower RMR and running EE in women. There are both sex and individual variations in changes in chemokine secretion in response to the same exercise situation and their associations with values of metabolic parameters.en
dc.description.statusPeer reviewed
dc.format.extent13
dc.format.extent3177538
dc.identifier.citationLagzdiņa, R, Rumaka, M, Gersone, G & Tretjakovs, P 2023, 'Circulating Levels of IL-8 and MCP-1 in Healthy Adults : Changes after an Acute Aerobic Exercise and Association with Body Composition and Energy Metabolism', International Journal of Molecular Sciences, vol. 24, no. 19, 14725. https://doi.org/10.3390/ijms241914725
dc.identifier.doi10.3390/ijms241914725
dc.identifier.issn1661-6596
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/15132
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85174721334&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofInternational Journal of Molecular Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectaerobic exercise
dc.subjectIL-8
dc.subjectMCP-1
dc.subjectmetabolism
dc.subject3.1 Basic medicine
dc.subject3.2 Clinical medicine
dc.subject3.3 Health sciences
dc.subject5.3 Educational sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectCatalysis
dc.subjectMolecular Biology
dc.subjectSpectroscopy
dc.subjectComputer Science Applications
dc.subjectPhysical and Theoretical Chemistry
dc.subjectOrganic Chemistry
dc.subjectInorganic Chemistry
dc.titleCirculating Levels of IL-8 and MCP-1 in Healthy Adults : Changes after an Acute Aerobic Exercise and Association with Body Composition and Energy Metabolismen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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