The effect of Ginkgo biloba and Camellia sinensis extracts on psychological state and glycemic control in patients with type 2 diabetes mellitus

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dc.contributor.authorLasaite, Lina
dc.contributor.authorSpadiene, Asta
dc.contributor.authorSavickiene, Nijole
dc.contributor.authorSkesters, Andrejs
dc.contributor.authorSilova, Alise
dc.contributor.institutionBioķīmijas zinātniskā laboratorija
dc.date.accessioned2021-08-13T09:25:01Z
dc.date.available2021-08-13T09:25:01Z
dc.date.issued2014-09
dc.descriptionPublisher Copyright: © 2014, Natural Product Incorporation. All rights reserved.
dc.description.abstractInterest in finding natural antioxidants for use in food or medical materials to prevent free radical imbalance has increased considerably over the past years. The aim of this research was to evaluate changes in glycemic control and psychological state of patients with type 2 diabetes mellitus (T2DM) after use of antioxidant plant preparations. Fifty-six patients with T2DM were randomly allocated to receive standardized Ginkgo biloba L. leaves dry extract, green tea dry extract, or placebo capsules. Diabetes glycemic control measured as glycated hemoglobin (HbA1c) level, antioxidant state and psychological data were evaluated at baseline, after 9 and 18 months of using either antioxidant preparations or placebo. The level of perceived stress lowered significantly after 9 months (p=0.038) and 18 months (p=0.030), and the psychological aspect of quality of life significantly improved after 18 months (p=0.019) of use of G. biloba extract. No significant differences were detected after using green tea extract. In patients using placebo, significant lowering of HbA1c level was observed after 18 months (p=0.017). In conclusion, antioxidant G. biloba leaf extract exhibited a mild effect on psychological state and a trend of improving glycemic control in patients with type 2 diabetes mellitus.en
dc.description.statusPeer reviewed
dc.format.extent6
dc.format.extent323589
dc.identifier.citationLasaite, L, Spadiene, A, Savickiene, N, Skesters, A & Silova, A 2014, 'The effect of Ginkgo biloba and Camellia sinensis extracts on psychological state and glycemic control in patients with type 2 diabetes mellitus', Natural Product Communications, vol. 9, no. 9, pp. 1345-1350. https://doi.org/10.1177/1934578x1400900931
dc.identifier.doi10.1177/1934578x1400900931
dc.identifier.issn1934-578X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/6002
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=84907501817&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofNatural Product Communications
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectEmotional state
dc.subjectGinkgo biloba L. extract
dc.subjectGreen tea ( Camellia sinensis L.) extract
dc.subjectPerceived stress
dc.subjectQuality of life
dc.subjectType 2 diabetes mellitus
dc.subject3.1 Basic medicine
dc.subject1.6 Biological sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectPharmacology
dc.subjectPlant Science
dc.subjectDrug Discovery
dc.subjectComplementary and alternative medicine
dc.subjectSDG 3 - Good Health and Well-being
dc.titleThe effect of Ginkgo biloba and Camellia sinensis extracts on psychological state and glycemic control in patients with type 2 diabetes mellitusen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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