What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque ?

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dc.contributor.authorLioznovs, Andrejs
dc.contributor.authorRadzina, Maija
dc.contributor.authorSaule, Laura
dc.contributor.authorGrinbergs, Peteris Einars
dc.contributor.authorLācis, Aigars
dc.contributor.institutionDepartment of Radiology
dc.date.accessioned2024-02-26T18:10:01Z
dc.date.available2024-02-26T18:10:01Z
dc.date.issued2024-03
dc.descriptionPublisher Copyright: © 2024 by the authors.
dc.description.abstractBackground and Objectives: Unstable atherosclerotic plaque in the arteries is one of the main risk factors for cerebral ischemia. Duplex ultrasound is a frequently used diagnostic method, but it has some limitations for microvascularization and neovascularization evaluation. The aim of this review was to evaluate the role of the new multiparametric US method—contrast-enhanced ultrasound (CEUS)—in atherosclerotic plaque instability verification. Materials and Methods: Original studies, reviews, and meta-analyses were included in this article. A total of 53 studies were retrieved; 29 were included in this study. Results: Carotid artery CEUS as a part of the multiparametric ultrasound method shows promising results and provides additional characteristics of soft- and high-risk atherosclerotic plaques; it can be advised in clinical practice for patients with carotid artery soft- and high-risk plaques. However, there are some limitations, such as extensive calcinosis with important acoustic shadows in carotid atherosclerotic plaque neovascularization diagnostics by CEUS. The added value of CEUS in the characterization of atherosclerotic plaque is that it indicates regions with high neovascularization and visualizes ulcerations on plaque surfaces, suggestive of increased instability risk.en
dc.description.statusPeer reviewed
dc.format.extent11
dc.format.extent484126
dc.identifier.citationLioznovs, A, Radzina, M, Saule, L, Grinbergs, P E & Lācis, A 2024, 'What Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque ?', Medicina (Kaunas), vol. 60, no. 3, 375, pp. 1-11. https://doi.org/10.3390/medicina60030375
dc.identifier.doi10.3390/medicina60030375
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/15334
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85188959330&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina (Kaunas)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectduplex Doppler ultrasonography
dc.subjectCEUS
dc.subjectunstable plaque
dc.subjectstenosis
dc.subjectneovascularization
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleWhat Is the Added Value of Carotid CEUS in the Characterization of Atherosclerotic Plaque ?en
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview

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