Latvian Healthcare Professionals’ Self-Reported Knowledge, Attitudes, and Behaviors Related to Pregnancy Prevention Program Materials for Valproate-Containing Medicines

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dc.contributor.authorŠpoģe, Milana
dc.contributor.authorKursīte, Mirdza
dc.contributor.authorPoplavska, Elita
dc.contributor.institutionDepartment of Applied Pharmacy
dc.contributor.institutionInstitute of Public Health
dc.date.accessioned2024-12-09T08:30:03Z
dc.date.available2024-12-09T08:30:03Z
dc.date.issued2024-12-04
dc.description.abstractBackground: Valproates are recognized for their significant teratogenic risks, which can lead to physical defects and developmental disorders when used during pregnancy. To mitigate these risks, the Pregnancy Prevention Program (PPP) was developed by European regulators for patients and healthcare professionals (HCPs). Despite the crucial nature of this program, the implementation of the PPP does not appear to be fully effective. This situation highlights the need for a deeper understanding of HCPs’ knowledge, attitudes, and behaviors regarding the PPP. Methods: A cross-sectional study using anonymous electronic questionnaires was conducted. The questionnaires were developed by a board of experts from eight different EU countries and were distributed among prescribers (general practitioners (GPs), neurologists, and psychiatrists) and pharmacists. Descriptive statistics were used to analyze the obtained data on participants’ knowledge, attitudes, and behaviors regarding the prescribing and dispensing of valproate-containing medicines to women of reproductive age, as well as the impact of PPP materials on their work. Results: The study results indicate that while HCPs in Latvia are generally aware of valproate teratogenic risks, significant gaps remain in the implementation of the PPP. A considerable number of both prescribers and pharmacists expressed the belief that they are not responsible for educating patients about the PPP, attributing this responsibility to other specialists. Furthermore, barriers such as a lack of time and accessible materials were identified. Conclusions: The roles and responsibilities of HCPs should be clearly defined to improve adherence to the PPP. Further research is needed to assess prescription and dispensing strategies, as well as HCPs’ attitudes toward the PPP. Additionally, re-evaluating and enhancing the accessibility of PPP materials is essential in effective risk management and better patient care.en
dc.description.statusPeer reviewed
dc.format.extent232290
dc.identifier.citationŠpoģe, M, Kursīte, M & Poplavska, E 2024, 'Latvian Healthcare Professionals’ Self-Reported Knowledge, Attitudes, and Behaviors Related to Pregnancy Prevention Program Materials for Valproate-Containing Medicines', Pharmacy, vol. 12, no. 6, 182. https://doi.org/10.3390/pharmacy12060182
dc.identifier.doi10.3390/pharmacy12060182
dc.identifier.issn2226-4787
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/16959
dc.identifier.urlhttps://www.mdpi.com/2226-4787/12/6/182
dc.identifier.urlhttps://www-webofscience-com.db.rsu.lv/wos/alldb/full-record/WOS:001383948100001
dc.language.isoeng
dc.relation.ispartofPharmacy
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectvalproates
dc.subjectPregnancy Prevention Program
dc.subjecthealthcare professionals
dc.subjectsurvey
dc.subject3.1 Basic medicine
dc.subject3.3 Health sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleLatvian Healthcare Professionals’ Self-Reported Knowledge, Attitudes, and Behaviors Related to Pregnancy Prevention Program Materials for Valproate-Containing Medicinesen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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