Circulation and Codetections of Influenza Virus, SARS-CoV-2, Respiratory Syncytial Virus, Rhinovirus, Adenovirus, Bocavirus, and Other Respiratory Viruses During 2022-2023 Season in Latvia
No Thumbnail Available
Date
2024-10
Journal Title
Journal ISSN
Volume Title
Publisher
Abstract
This retrospective study analysed the routine data obtained by multiplex real-time RT-qPCR methods for respiratory virus detection. A total of 4814 respiratory specimens collected during 1 September 2022-31 August 2023 were included in the study. A total of 38% of the specimens were positive for at least one target, with the incidence maximum (82%) for the small children (age group 0-4 years). The five dominant virus groups were rhinovirus (RV, 12%), influenza virus A (IAV, 7%), adenovirus (AdV, 6%), respiratory syncytial virus (RSV, 5%), and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, 5%). The specimens with multi-detections represented 19% of the positives, unevenly distributed (n = 225, 56, 43, 24) among the age groups 0-4, 5-14, 15-64, and 65< years, respectively. The dominant virus groups in multi-positive specimens were RV (53%), AdV (43%), and bocavirus (BoV, 35%)-in mutual pairs as well as all three together-followed by RSV (21%), and IAV (15%). Our study focused on the specimens with codetections and provides an insight into the variety of the respiratory virus interactions in Latvia during the first year since pandemic-related social restriction measures were eased. The observations also emphasise the need to consider the differentiation between rhinoviruses and enteroviruses, especially for the youngest patients in the age group 0-4.
Description
Publisher Copyright: © 2024 by the authors.
Keywords
Humans, Latvia/epidemiology, Child, Preschool, Child, Infant, Retrospective Studies, Adolescent, Rhinovirus/isolation & purification, Respiratory Tract Infections/virology, Adenoviridae/isolation & purification, Infant, Newborn, Adult, Seasons, SARS-CoV-2/genetics, Middle Aged, Aged, Young Adult, Male, COVID-19/virology, Female, Bocavirus/isolation & purification, Respiratory Syncytial Viruses/isolation & purification, Coinfection/virology, Orthomyxoviridae/isolation & purification, 3.2 Clinical medicine, 3.3 Health sciences, 1.1. Scientific article indexed in Web of Science and/or Scopus database
Citation
Kampenusa, I, Niedre-Otomere, B, Trofimova, J, Pole, I, Pakarna, G, Savicka, O & Nikisins, S 2024, 'Circulation and Codetections of Influenza Virus, SARS-CoV-2, Respiratory Syncytial Virus, Rhinovirus, Adenovirus, Bocavirus, and Other Respiratory Viruses During 2022-2023 Season in Latvia', Viruses, vol. 16, no. 11, 1650. https://doi.org/10.3390/v16111650