Maternal age-associated congenital anomalies among newborns : A retrospective study in Latvia

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dc.contributor.authorZile, Irisa
dc.contributor.authorVilleruĊĦa, Anita
dc.contributor.institutionRÄĞga StradiĊ†ĊĦ University
dc.contributor.institutionDepartment of Public Health and Epidemiology
dc.date.accessioned2021-05-13T08:10:01Z
dc.date.available2021-05-13T08:10:01Z
dc.date.issued2013
dc.description.abstractBackground and Objective: In Latvia, the mean age of women giving birth increased from 27.3 in 2000 to 29.0 years in 2010 during the last 11 years. The aim of this study was to report on major congenital anomalies of newborns at birth by the maternal age and to compare the mean maternal age by different diagnosis subgroups and maternal and neonatal characteristics. Material and Methods: A cross-sectional retrospective study with the data from the Medical Birth Register (2000-2010) was carried out. The live birth prevalence rate was calculated for the subgroups of major congenital anomalies per 10 000 live births by the maternal age. Results: The live birth prevalence rate of major congenital anomalies during the period 2000-2010 was 211.4 per 10 000 live births. The prevalence rate increased depending on the maternal age. Congenital heart defects, limb defects, and urinary system anomalies were the most common anomalies. The study results showed an age-related risk of abdominal wall defects, orofacial clefts, and chromosomal anomalies. There were significantly higher proportions of preterm births, newborns with low birth weight, and complications during pregnancy among mothers aged 35 years and more. Conclusions: The data on congenital anomalies from the Latvian Medical Birth Register can be used for the assessment of epidemiology of congenital anomalies. The results of this retrospective study showed a decrease in the live birth prevalence rate of major congenital anomalies despite an increase in the mean age of mothers in Latvia.en
dc.description.statusPeer reviewed
dc.format.extent7
dc.format.extent257948
dc.identifier.citationZile, I & VilleruĊĦa, A 2013, 'Maternal age-associated congenital anomalies among newborns : A retrospective study in Latvia', Medicina (Lithuania), vol. 49, no. 1, pp. 29-35. https://doi.org/10.3390/medicina49010006
dc.identifier.doi10.3390/medicina49010006
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/4222
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=84884246476&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina (Lithuania)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCongenital anomalies
dc.subjectMaternal age
dc.subjectNewborns
dc.subjectPrevalence rate
dc.subject3.3 Health sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral Medicine
dc.titleMaternal age-associated congenital anomalies among newborns : A retrospective study in Latviaen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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