Whole Brain and Corpus Callosum Fractional Anisotropy Differences in Patients with Cognitive Impairment

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dc.contributor.authorKaļva, Kalvis
dc.contributor.authorZdanovskis, Nauris
dc.contributor.authorŠneidere, Kristīne
dc.contributor.authorKostiks, Andrejs
dc.contributor.authorKarelis, Guntis
dc.contributor.authorPlatkājis, Ardis
dc.contributor.authorStepens, Ainārs
dc.contributor.institutionDepartment of Radiology
dc.contributor.institutionMilitārās medicīnas pētījumu un studiju centrs
dc.contributor.institutionDepartment of Health Psychology and Paedagogy
dc.contributor.institutionDepartment of Infectology
dc.date.accessioned2024-01-10T10:10:01Z
dc.date.available2024-01-10T10:10:01Z
dc.date.issued2023-12-16
dc.descriptionPublisher Copyright: © 2023 by the authors.
dc.description.abstractDiffusion tensor imaging (DTI) is an MRI analysis method that could help assess cognitive impairment (CI) in the ageing population more accurately. In this research, we evaluated fractional anisotropy (FA) of whole brain (WB) and corpus callosum (CC) in patients with normal cognition (NC), mild cognitive impairment (MCI), and moderate/severe cognitive impairment (SCI). In total, 41 participants were included in a cross-sectional study and divided into groups based on Montreal Cognitive Assessment (MoCA) scores (NC group, nine participants, MCI group, sixteen participants, and SCI group, sixteen participants). All participants underwent an MRI examination that included a DTI sequence. FA values between the groups were assessed by analysing FA value and age normative percentile. We did not find statistically significant differences between the groups when analysing CC FA values. Both approaches showed statistically significant differences in WB FA values between the MCI-SCI and MCI-NC groups, where the MCI group participants showed the highest mean FA and highest mean FA normative percentile results in WB.en
dc.description.statusPeer reviewed
dc.format.extent1962809
dc.identifier.citationKaļva, K, Zdanovskis, N, Šneidere, K, Kostiks, A, Karelis, G, Platkājis, A & Stepens, A 2023, 'Whole Brain and Corpus Callosum Fractional Anisotropy Differences in Patients with Cognitive Impairment', Diagnostics, vol. 13, no. 24, 3679. https://doi.org/10.3390/diagnostics13243679
dc.identifier.doi10.3390/diagnostics13243679
dc.identifier.issn2075-4418
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/15095
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85180728555&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofDiagnostics
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectdiffusion tensor imaging
dc.subjectMontreal Cognitive Assessment
dc.subjectfractional anisotropy
dc.subjectcognitive impairment
dc.subjectneuroradiology
dc.subjectcognition
dc.subjectmild cognitive impairment
dc.subjectdementia
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleWhole Brain and Corpus Callosum Fractional Anisotropy Differences in Patients with Cognitive Impairmenten
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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