The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation

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dc.contributor.authorVamze, J.
dc.contributor.authorPilmane, M.
dc.contributor.authorSkagers, A.
dc.contributor.institutionRīga Stradiņš University
dc.contributor.institutionInstitute of Anatomy and Anthropology
dc.date.accessioned2023-03-28T14:40:01Z
dc.date.available2023-03-28T14:40:01Z
dc.date.issued2012
dc.description.abstractBone loss induced by inflammation is one of the complications after biomaterial implantation. There is no much data on expression of cytokines and defensins into the bone tissue around the implants in literature. The aim of this work was to investigate the distribution and appearance of interleukin (IL)-1, IL-6, IL-8, IL10 and β – defensin (BD)-2, BD-3, BD-4 after the implantation of different biomaterials. Bone developing zones, signs of bone-implant contact and low expression of pro-inflammatory cytokine IL-1, IL-6 and anti-inflammatory cytokine IL-10 in experimental tissue with pure HAp and unburned HAp implants indicate a potential advantage of this material in terms of its biocompatibility over the other materials used in our study.en
dc.description.statusPeer reviewed
dc.format.extent894885
dc.identifier.citationVamze, J, Pilmane, M & Skagers, A 2012, The expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantation. in International Conference "Functional Materials and Nanotechnologies" (FM &NT-2012) : Conference Proceedings. vol. 38, 012025, IOP Conference Series: Materials Science and Engineering, International Conference "Functional Materials and Nanotechnologies" (FM &NT-2012), Riga, Latvia, 17/04/12.
dc.identifier.citationconference
dc.identifier.issn1757-8981
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/11241
dc.identifier.urlhttps://iopscience.iop.org/article/10.1088/1757-899X/38/1/012025/pdf
dc.identifier.urlhttps://www-scopus-com.db.rsu.lv/record/display.uri?eid=2-s2.0-84874050919&origin=AuthorNamesList&txGid=a325a4600080b5f9c8094b7900d31651&isValidNewDocSearchRedirection=false
dc.language.isoeng
dc.relation.ispartofInternational Conference "Functional Materials and Nanotechnologies" (FM&NT-2012)
dc.relation.ispartofseriesIOP Conference Series: Materials Science and Engineering
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject1.6 Biological sciences
dc.subject2.6 Medical engineering
dc.subject3.1. Articles or chapters in proceedings/scientific books indexed in Web of Science and/or Scopus database
dc.titleThe expression of cytokines and beta -defensin 2,-3,-4 in rabbit bone tissue after hydroxyapatite (HAp), alpha-Tricalcium phosphate (alpha-TCP) and polymethylmethacrylate (PMMA) implantationen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontobookanthology/conference

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