The relationship between seropositivity against Chlamydia pneumoniae and stroke and its subtypes in a Latvian population

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dc.contributor.authorKenina, Viktorija
dc.contributor.authorAuce, Pauls
dc.contributor.authorMillers, Andrejs
dc.contributor.institutionDepartment of Neurology and Neurosurgery
dc.date.accessioned2021-08-18T06:55:01Z
dc.date.available2021-08-18T06:55:01Z
dc.date.issued2011
dc.description.abstractBackground and Objective: Serological evidence of infection with Chlamydia pneumoniae has been associated with cardiovascular diseases, but the relationship with stroke and its risk factors remains not completely understood. The aim of this study was to determine whether serological evidence of infection with Chlamydia pneumoniae was associated with the risk of ischemic stroke and any of investigated stroke subtypes. Material and Methods: Confirmed stroke cases (n=102) were compared with gender- and agematched control patients (n=48). The patients with stroke were divided into 3 groups according to the TOAST criteria: atherothrombotic (n=36), cardioembolic (n=47), and of undetermined etiology (n=19). Plasma levels of IgG antibodies to Chlamydia pneumoniae were measured by enzymelinked immunosorbent assay. Results: There was a significant association between seropositivity to Chlamydia pneumoniae and stroke. Anti-Chlamydia pneumoniae IgG antibodies were detected in 64 case patients (62.7%) and 17 control patients (35.4%) (χ2=9.8; df=1; P=0.002). IgG seropositivity to Chlamydia pneumoniae was linked to all the analyzed etiological subtypes of stroke. Conclusion: This study showed that IgG seropositivity to Chlamydia pneumoniae was associated with stroke and all the analyzed etiological subtypes of stroke.en
dc.description.statusPeer reviewed
dc.format.extent4
dc.format.extent206386
dc.identifier.citationKenina, V, Auce, P & Millers, A 2011, 'The relationship between seropositivity against Chlamydia pneumoniae and stroke and its subtypes in a Latvian population', Medicina, vol. 47, no. 12, pp. 657-660. https://doi.org/10.3390/medicina47120096
dc.identifier.doi10.3390/medicina47120096
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/6025
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=84859029363&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCerebrovascular disease
dc.subjectChlamydia pneumoniae
dc.subjectRisk factor
dc.subjectStroke
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral Medicine
dc.subjectSDG 3 - Good Health and Well-being
dc.titleThe relationship between seropositivity against Chlamydia pneumoniae and stroke and its subtypes in a Latvian populationen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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