Selective transepithelial ablation with simultaneous accelerated corneal crosslinking for corneal regularization of keratoconus : STARE-X protocol

Simple item page
dc.contributor.authorRechichi, Miguel
dc.contributor.authorMazzotta, Cosimo
dc.contributor.authorOliverio, Giovanni William
dc.contributor.authorRomano, Vito
dc.contributor.authorBorroni, Davide
dc.contributor.authorFerrise, Marco
dc.contributor.authorBagaglia, Simone
dc.contributor.authorJacob, Soosan
dc.contributor.authorMeduri, Alessandro
dc.contributor.institutionDepartment of Ophthalmology
dc.date.accessioned2022-02-22T13:20:04Z
dc.date.available2022-02-22T13:20:04Z
dc.date.issued2021-11-01
dc.descriptionPublisher Copyright: Copyright © 2021 The Author(s). Published by Wolters Kluwer Health, Inc. on behalf of ASCRS and ESCRS.
dc.description.abstractPURPOSE: To evaluate the changes in refractive outcomes and corneal aberrations in central and paracentral keratoconus after selective transepithelial topography-guided photorefractive keratectomy combined with accelerated corneal crosslinking (STARE-X). SETTINGS: Centro Polispecialistico Mediterraneo, Siena Crosslinking Center, and University of Messina, Italy. DESIGN: Prospective, interventional, multicentric study. METHODS: Patients were subdivided into 2 groups: Group 1 with cone located within the central 3 mm zone (50 eyes) and Group 2 (50 eyes) with cone located outside the central 3 mm zone. Follow-up was 2 years at least for all eyes. Outcome parameters included uncorrected distance visual acuity (UDVA) and corrected distance visual acuity (CDVA). Corneal tomography and corneal wavefront aberrations were assessed and compared before and 2 years after the treatment. RESULTS: 100 eyes of 100 patients underwent STARE-X protocol. At 2 years, UDVA and CDVA improved, and sphere, cylinder, and Kmax reduced after treatment in both groups (P < .001, respectively). Moreover, a statistically significant reduction was observed of total higher-order aberrations root main square (RMS), coma RMS, and spherical aberration RMS in both groups (P < .001, respectively). However, CDVA improved more in Group 1 than in Group 2 (P < .02). CONCLUSIONS: The STARE-X protocol demonstrated effective results in halting keratoconus progression and improving corneal regularity with a safe and effective profile. STARE-X improved both visual acuity and corneal aberration at 2 years. Longer follow-up studies are warranted to observe further long-term CXL flattening effect on the cone.en
dc.description.statusPeer reviewed
dc.format.extent8
dc.format.extent666656
dc.identifier.citationRechichi, M, Mazzotta, C, Oliverio, G W, Romano, V, Borroni, D, Ferrise, M, Bagaglia, S, Jacob, S & Meduri, A 2021, 'Selective transepithelial ablation with simultaneous accelerated corneal crosslinking for corneal regularization of keratoconus : STARE-X protocol', Journal of Cataract and Refractive Surgery, vol. 47, no. 11, pp. 1403-1410. https://doi.org/10.1097/j.jcrs.0000000000000640
dc.identifier.doi10.1097/j.jcrs.0000000000000640
dc.identifier.issn0886-3350
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/7636
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85111290997&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofJournal of Cataract and Refractive Surgery
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectSurgery
dc.subjectOphthalmology
dc.subjectSensory Systems
dc.titleSelective transepithelial ablation with simultaneous accelerated corneal crosslinking for corneal regularization of keratoconus : STARE-X protocolen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Selective_transepithelial_ablation_with.pdf
Size:
651.03 KB
Format:
Adobe Portable Document Format
Download

Collections

Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure