The Impact of Food Additives on Gut Homeostasis and their Potential Contribution to the Development of Inflammatory Bowel Disease
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Date
2020
Authors
Journal Title
Journal ISSN
Volume Title
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Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Rūpnieciski attīstītajās sabiedrībās pēdējās desmitgadēs ir pieaudzis īpaši pārstrādātas pārtikas un pārtikas piedevu patēriņš, kas ir nonācis ikdienas pārtikas produktos. Vienlaicīgi pēdējos gados ir palielinājies zarnu un sistēmisko imūno-iekaisuma traucējumu biežums iepriekš zemas slimības sastopamības apgabalos, piemēram, Āzijā, iespējams, pateicoties šo sabiedrību rietumnieci skumām. Lai gan precīza zarnu iekaisuma slimības patofizioloģija joprojām nav zināma, to attīstību ietekmē ģenētikas, imūnsistēmas un tādu vides faktoru kā diēta mijiedarbība. Šī literatūras pārskata mērķis ir apspriest dažu biežāk sastopamo pārtikas piedevu lomu zarnu homeostāzē un to iespējamo nozīmi zarnu iekaisuma attīstībā.
Consumption of ultra-processed food has increased over the last decades, particularly in industrialized societies, and the escalating consumption of food additives has found its way into everyday foods. Simultaneously in the last years, so has the frequency of intestinal and systemic immune-inflammatory disorders in previously low incidence areas such as Asia, likely due to the Westernization of these societies. Although the exact pathophysiology of inflammatory bowel disease remains unknown, the development is influenced by the interplay between genetics, the immune system and environmental factors such as diet. This literary review aims to discuss the role that some of the more common food additives play on gut homeostasis and their potential contribution to inflammatory bowel disease development
Consumption of ultra-processed food has increased over the last decades, particularly in industrialized societies, and the escalating consumption of food additives has found its way into everyday foods. Simultaneously in the last years, so has the frequency of intestinal and systemic immune-inflammatory disorders in previously low incidence areas such as Asia, likely due to the Westernization of these societies. Although the exact pathophysiology of inflammatory bowel disease remains unknown, the development is influenced by the interplay between genetics, the immune system and environmental factors such as diet. This literary review aims to discuss the role that some of the more common food additives play on gut homeostasis and their potential contribution to inflammatory bowel disease development
Description
Medicīna
Medicine
Veselības aprūpe
Health Care
Medicine
Veselības aprūpe
Health Care
Keywords
Food additives, Inflammatory bowel disease, Gut homeostasis