Viewpoints Nowadays about Ethiology of Burning Mouth Syndrome
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Date
2021
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Mērķis: Šī pētījuma mērķis bija apkopot jaunākos datus par dedzinošās mutes sindroma etioloģiju.
Ievads: Dedzinošās mutes sindroms ir hronisks idiopātisks mutes dobuma sāpju stāvoklis, ko raksturo nepārtraukta intraorāla dedzināšana bez jebkādas klīniski redzamas mutes dobuma patoloģijas. Dedzinošas mutes sindroma etioloģija un patogenitāte joprojām ir slikti izprasta. Ir zināms, ka etioloģija ir daudzveidīga ar neiropātiskām īpašībām, bet ir nepieciešama turpmāka izpēte, lai iegūtu labāku izpratni par šo reto un sarežģīto sāpju stāvokli.
Materiāli un metodes: Tika veikta datu apkopošana, izmantojot pieejamās tiešsaistes datu bāzes. Tika iekļauti tikai raksti, kas publicēti angļu valodā no pēdējiem sešiem gadiem.
Rezultāti: ŠI pētījuma rezultāti ir literatūras pārskati par jaunākajiem pierādījumiem par BMS etioloģiju un ar to saistītajiem faktoriem, kas varētu veicināt BMS attīstību.
Secinājumi: pierādījumi par BMS neiropātiskajām īpašībām ir labi dokumentēti, bet precīzs mehānisms, kas raksturotu patoloģiskas izmaiņas nervu sistēmā, paliek nezināms (1). Hormonālās izmaiņas var izraisīt neiroprotektīvo steroīdu samazināšanos, izraisot disfunkciju trigeminālā sistēmā (2), bet iekaisuma (3), psihogēna (4) un ģenētiska faktora (5) nozīme dedzinošas mutes sindroma etioloģijā joprojām ir neskaidra. Ir nepieciešami kvalitatīvāki pētījumi, sistemātiski diagnostikas kritēriji, kā arī uz pierādījumiem balstītas, standartizētas ārstēšanas vadlīnijas (6).
Goal: The goal of this study was to gather and summarize recent evidence on the etiology of burning mouth syndrome. Overview: Burning mouth syndrome (BMS) is a chronic idiopathic orofacial pain condition characterized by persisting intraoral burning without any clinically evident oral pathology. The etiology and pathogenesis of BMS remains poorly understood. The current view is that the etiology of BMS is multifactorial with neuropathic characteristics, but further research is required for gaining better understanding on this rare and complex pain condition. Materials and methods: A throughout literature search was conducted using available online databases. Only articles published in English from the last six years were included. Results: The results of this study consist of literature review on the recent evidence on the etiology of BMS and associated factors that could contribute to the development of BMS. Conclusions: The evidence on the neuropathic characteristics of BMS is well documented, but the exact mechanism leading to pathological changes within the nervous system remains unknown (1). Hormonal changes could result in depletion of neuroprotective steroids causing dysfunction within the trigeminal system (2) while the role of inflammation (3), psychogenic (4) and genetic factors (5) in the etiology of BMS remains unclear. In the field of BMS, there is a need for higher quality research, systematic diagnostic criteria as well as evidence-based, standardized treatment guidelines (6).
Goal: The goal of this study was to gather and summarize recent evidence on the etiology of burning mouth syndrome. Overview: Burning mouth syndrome (BMS) is a chronic idiopathic orofacial pain condition characterized by persisting intraoral burning without any clinically evident oral pathology. The etiology and pathogenesis of BMS remains poorly understood. The current view is that the etiology of BMS is multifactorial with neuropathic characteristics, but further research is required for gaining better understanding on this rare and complex pain condition. Materials and methods: A throughout literature search was conducted using available online databases. Only articles published in English from the last six years were included. Results: The results of this study consist of literature review on the recent evidence on the etiology of BMS and associated factors that could contribute to the development of BMS. Conclusions: The evidence on the neuropathic characteristics of BMS is well documented, but the exact mechanism leading to pathological changes within the nervous system remains unknown (1). Hormonal changes could result in depletion of neuroprotective steroids causing dysfunction within the trigeminal system (2) while the role of inflammation (3), psychogenic (4) and genetic factors (5) in the etiology of BMS remains unclear. In the field of BMS, there is a need for higher quality research, systematic diagnostic criteria as well as evidence-based, standardized treatment guidelines (6).
Description
Zobārstniecība
Dentistry
Veselības aprūpe
Health Care
Dentistry
Veselības aprūpe
Health Care
Keywords
Dedzinošās mutes sindroms, primārā tipa dedzinošās mutes sindroms, glossodīnija, neiropātiskas sāpes mutes dobumā, etioloģiskie faktori, Burning mouth syndrome, BMS, primary burning mouth syndrome, glossodynia, orofacial neuropathic pain, etiological factors