Safety Concerns Related to the Simultaneous Use of Prescription or Over-the-Counter Medications and Herbal Medicinal Products : Survey Results among Latvian Citizens

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dc.contributor.authorSile, Inga
dc.contributor.authorTeterovska, Renate
dc.contributor.authorOnzevs, Oskars
dc.contributor.authorArdava, Elita
dc.contributor.institutionDepartment of Applied Pharmacy
dc.contributor.institutionDepartment of Pharmaceutical Chemistry
dc.contributor.institutionRed Cross Medical College of Rīga Stradiņš University
dc.date.accessioned2023-08-25T08:10:01Z
dc.date.available2023-08-25T08:10:01Z
dc.date.issued2023-08-09
dc.descriptionFunding Information: This work was supported by the RSU Red Cross Medical College scientific research project “The use of medicines, nutritional supplements and herbal preparations in Latvia and the associated risks to the patient’s health” (Nr. 2-30/2019/069). Publisher Copyright: © 2023 by the authors.
dc.description.abstractThe use of herbal medicines is increasing worldwide. While the safety profile of many herbal medicines is promising, the data in the literature show important interactions with conventional drugs that can expose individual patients to high risk. The aim of this study was to investigate the experience of the use of herbal medicines and preparations and the risks of interactions between herbal and conventional medicines among Latvian citizens. Data were collected between 2019 and 2021 using a structured questionnaire designed for pharmacy customers in Latvia. Electronic databases such as Drugs.com, Medscape, and European Union herbal monographs were reviewed for the risk of drug interactions and potential side effects when herbal medicines were involved. The survey included 504 respondents. Of all the participants, 77.8% used herbal preparations. Most of the participants interviewed used herbal remedies based on the recommendation of the pharmacist or their own initiative. A total of 38.3% found the use of herbal remedies safe and harmless, while 57.3% of respondents regarded the combination of herbal and regular drugs as unsafe. The identified herbal medicines implicated in the potential risk of serious interactions were grapefruit, St. John’s wort, and valerian. As the risks of herb–drug interactions were identified among the respondents, in the future, both pharmacy customers and healthcare specialists should pay more attention to possible herb–drug interactions of over-the-counter and prescription medications.en
dc.description.statusPeer reviewed
dc.format.extent1344404
dc.identifier.citationSile, I, Teterovska, R, Onzevs, O & Ardava, E 2023, 'Safety Concerns Related to the Simultaneous Use of Prescription or Over-the-Counter Medications and Herbal Medicinal Products : Survey Results among Latvian Citizens', International Journal of Environmental Research and Public Health, vol. 20, no. 16, 6551. https://doi.org/10.3390/ijerph20166551
dc.identifier.doi10.3390/ijerph20166551
dc.identifier.issn1661-7827
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/14850
dc.identifier.urlhttps://www.webofscience.com/wos/alldb/full-record/MEDLINE:37623137
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85168716898&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofInternational Journal of Environmental Research and Public Health
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectadverse drug effects
dc.subjectconsumer attitude
dc.subjectpharmacy
dc.subjectherbal medicines
dc.subjectherb–drug interactions
dc.subject3.1 Basic medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleSafety Concerns Related to the Simultaneous Use of Prescription or Over-the-Counter Medications and Herbal Medicinal Products : Survey Results among Latvian Citizensen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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