Acute Ischemic Stroke Endovascular Treatment of Patients with Large Vessel Occlusions

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dc.contributor.authorBalodis, Arturs
dc.contributor.authorRadzina, Maija
dc.contributor.authorMiglāne, Evija
dc.contributor.authorValante, Ramona
dc.contributor.authorMillers, Andrejs
dc.contributor.authorKupčs, Kārlis
dc.contributor.institutionRīga Stradiņš University
dc.contributor.institutionDepartment of Neurology and Neurosurgery
dc.date.accessioned2021-06-02T06:30:01Z
dc.date.available2021-06-02T06:30:01Z
dc.date.issued2015-01-01
dc.descriptionPublisher Copyright: © 2015 by Arturs Balodis.
dc.description.abstractMechanical thrombectomy as an active treatment method has recently been chosen for patients with large artery occlusions and thrombolysis beyond a time window. The aim of our study was to evaluate the results of endovascular treatment in patients with proximal vessel occlusion, compare this group with the intravenous thrombolysis group, and to identify possible criteria of active treatment. The prospective study included 81 patients hospitalised in the Pauls Stradiņš Clinical University Hospital due to acute ischemic stroke; 48 of them received mechanical thrombectomy and 33-intravenous thrombolysis. Thrombectomy (TE) was performed using Solitaire FR stent retrievers. The NIHSS score was used for evaluation of early therapy results and mRS (modified Rankin Scale) was used for late therapy results. ASPECTS was used to define the lesion size using imaging on admission and after treatment. Median NIHSS on admission was higher in the TE group-16 (range 12 to 19) than in the TL group-12 (range 8 to 15) (p < 0.05). Ninety days after treatment, mRS (0-2) was seen in 67% of patients in the TE group (n = 29), and 34% of patients in the TL group (n = 9) patients (p < 0.05). Median ASPECTS was lower in TE group-5, in comparison to the TL group-7 (p < 0.01) Mortality frequency was higher in the TL group (p > 0.05). Frequency of symptomatic intracerebral haemorrhages was similar in the groups. Mechanical thrombectomy can achieve better late functional outcome than thrombolysis in a selected patients group.en
dc.description.statusPeer reviewed
dc.format.extent5
dc.format.extent239691
dc.identifier.citationBalodis, A, Radzina, M, Miglāne, E, Valante, R, Millers, A & Kupčs, K 2015, 'Acute Ischemic Stroke Endovascular Treatment of Patients with Large Vessel Occlusions', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 69, no. 5, pp. 205-209. https://doi.org/10.1515/prolas-2015-0030
dc.identifier.doi10.1515/prolas-2015-0030
dc.identifier.issn1407-009X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/4661
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=84948147845&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcriteria of active treatment
dc.subjectischemic stroke
dc.subjectthrombectomy
dc.subjectthrombolysis
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral
dc.titleAcute Ischemic Stroke Endovascular Treatment of Patients with Large Vessel Occlusionsen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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