Sudden onset orthostatic dysarthria as a presenting symptom of bulbar onset myasthenia gravis : a video case report

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dc.contributor.authorOsipovs, Jānis Dāvis
dc.contributor.authorŠankova, Eva
dc.contributor.authorKarelis, Guntis
dc.contributor.authorŽelve, Ziedīte
dc.contributor.authorPolunosika, Elīna
dc.contributor.authorSavicka, Līga
dc.contributor.institutionRīga Stradiņš University
dc.date.accessioned2025-01-06T10:40:01Z
dc.date.available2025-01-06T10:40:01Z
dc.date.issued2025-01-01
dc.description.abstractMyasthenia gravis (MG) is a rare autoimmune neuromuscular disorder that can present with various early clinical symptoms and signs. The diagnosis of MG with bulbar symptom onset can be clinically challenging for clinicians with limited experience with neuromuscular disorders. This case report presents an elderly patient with an abrupt onset of orthostatic dysarthria, in whom a high level of diagnostic suspicion leads to a short period until confirmation of diagnosis. This clinical case shows symptomatic treatment initiation on the 4th day after the onset of symptoms in a patient with bulbar onset MG. Serologic confirmation of MG was received on the 11th hospitalisation day. This case report contains a short video of the evaluation of orthostatic dysarthria. Orthostatic dysarthria is a rare presentation symptom for bulbar onset MG. Information on the evaluation of orthostatic dysarthria is sparse. Considering that bulbar onset MG can be a life-threatening condition, we would like to share our positive experience of rapid diagnosis and successful treatment.en
dc.description.statusPeer reviewed
dc.format.extent3
dc.format.extent334680
dc.identifier.citationOsipovs, J D, Šankova, E, Karelis, G, Želve, Z, Polunosika, E & Savicka, L 2025, 'Sudden onset orthostatic dysarthria as a presenting symptom of bulbar onset myasthenia gravis : a video case report', Neuroimmunology Reports, vol. 7, 100235. https://doi.org/10.1016/j.nerep.2024.100235
dc.identifier.doi10.1016/j.nerep.2024.100235
dc.identifier.issn2667-257X
dc.identifier.otherunpaywall: 10.1016/j.nerep.2024.100235
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/17016
dc.language.isoeng
dc.relation.ispartofNeuroimmunology Reports
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectMyasthenia gravis
dc.subjectOrthostatic dysarthria
dc.subjectNeostigmine test
dc.subjectAcetylcholine receptor antibodies
dc.subjectCase report
dc.subject3.2 Clinical medicine
dc.subject3.3 Health sciences
dc.subject1.3. Anonymously reviewed scientific article published in a journal with an international editorial board and is available in another indexed database
dc.titleSudden onset orthostatic dysarthria as a presenting symptom of bulbar onset myasthenia gravis : a video case reporten
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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