Occurrence of Cryptosporidium spp. and Giardia spp. Infection in Humans in Latvia : Evidence of Underdiagnosed and Underreported Cases

Simple item page
dc.contributor.authorDeksne, Gunita
dc.contributor.authorKrūmiņš, Agris
dc.contributor.authorMateusa, Maira
dc.contributor.authorMorozovs, Vladimirs
dc.contributor.authorŠveisberga , Dārta Paula
dc.contributor.authorKarotinska, Rita
dc.contributor.authorBormane, Antra
dc.contributor.authorVīksna, Ludmila
dc.contributor.authorKrūmiņa, Angelika
dc.contributor.institutionFaculty of Medicine
dc.date.accessioned2022-08-16T21:02:47Z
dc.date.available2022-08-16T21:02:47Z
dc.date.issued2022-04
dc.descriptionFunding Information: Funding: This research was funded by the Fundamental and applied research “Transmission of Foodborne Parasitic pathogen from animals to humans: TRANSPAR” (lzp-2021/1-0055) and financed by the Ministry of Education and Science, Latvia. Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.
dc.description.abstractBackground and Objectives: Protozoan parasites—Cryptosporidium and Giardia—are important causes of diarrhea with an underestimated short-term burden on childhood growth and wellbeing in children under five years of age. The main transmission routes for both parasites are food and drinking water; transmission from person to person; and, due to their zoonotic nature, from domestic or wild animals to humans. The aims of the present study were to summarize the officially reported human cases of cryptosporidiosis and giardiasis in Latvia and to assess the occurrence of Cryptosporidium and Giardia in children within a prospective prevalence study. Materials and Methods: The number of officially reported cases of cryptosporidiosis and giardiasis in the time period of 2000–2020 was collected from the Centre for Disease Prevention and Control of Latvia. Data from a clinical diagnostic laboratory were included in the study in the period from 1 January 2008 to 31 December 2018. Additionally, a prospective study was performed, and fecal samples were collected from unique 0–17-year-old patients from January to February 2021 and tested using fluorescent microscopy. Results: Overall, during the 20-year period, 71 cases (mean per year = 9) of cryptosporidiosis and 1020 (mean per year = 34) cases of giardiasis were officially reported in Latvia. Meanwhile, within the prospective study, we found 35 (6.0%; 95%CI 4.3–8.1) Cryptosporidium and 42 (7.2%; 95%CI 5.3–9.6) Giardia cases. Conclusions: Here, we provide clear proof that both Cryptosporidium and Giardia are underdiagnosed in Latvia, which could also be true for neighboring Baltic and European countries, where a low number of cases are officially reported. Therefore, we highlight the hypothesis that the actual number of cryptosporidiosis and giardiasis human cases in the Baltic states is higher than that officially reported, including in Latvia.en
dc.description.statusPeer reviewed
dc.format.extent687772
dc.identifier.citationDeksne, G, Krūmiņš, A, Mateusa, M, Morozovs, V, Šveisberga , D P, Karotinska, R, Bormane, A, Vīksna, L & Krūmiņa, A 2022, 'Occurrence of Cryptosporidium spp. and Giardia spp. Infection in Humans in Latvia : Evidence of Underdiagnosed and Underreported Cases', Medicina (Kaunas), vol. 58, no. 4, 471. https://doi.org/10.3390/medicina58040471
dc.identifier.doi10.3390/medicina58040471
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/9394
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85127682574&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina (Kaunas)
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCryptosporidiosis
dc.subjectgiardiasis
dc.subjectchildren
dc.subjectunderdiagnosed
dc.subjectThe Baltic States
dc.subject3.2 Clinical medicine
dc.subject3.3 Health sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectSDG 3 - Good Health and Well-being
dc.titleOccurrence of Cryptosporidium spp. and Giardia spp. Infection in Humans in Latvia : Evidence of Underdiagnosed and Underreported Casesen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

Files

Original bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
Occurrence_of_Cryptosporidium_spp..pdf
Size:
671.65 KB
Format:
Adobe Portable Document Format
Download

Collections

Research outputs from Pure / Zinātniskās darbības rezultāti no ZDIS Pure