The European ME/CFS Biomarker Landscape project : An initiative of the European network EUROMENE

Abstract

Myalgic encephalomyelitis or chronic fatigue syndrome (ME/CFS) is a common and severe disease with a considerable social and economic impact. So far, the etiology is not known, and neither a diagnostic marker nor licensed treatments are available yet. The EUROMENE network of European researchers and clinicians aims to promote cooperation and advance research on ME/CFS. To improve diagnosis and facilitate the analysis of clinical trials surrogate markers are urgently needed. As a first step for developing such biomarkers for clinical use a database of active biomarker research in Europe was established called the ME/CFS EUROMENE Biomarker Landscape project and the results are presented in this review. Further we suggest strategies to improve biomarker development and encourage researchers to take these into consideration for designing and reporting biomarker studies.

Description

Publisher Copyright: © 2017 The Author(s). Copyright: Copyright 2018 Elsevier B.V., All rights reserved.

Keywords

Autoantibodies, Autoimmunity, B cell, Biomarker, Cytokines, Diagnostic, European network, Landscape project, ME/CFS, Viral, 1.6 Biological sciences, 3.3 Health sciences, 1.1. Scientific article indexed in Web of Science and/or Scopus database, General Biochemistry,Genetics and Molecular Biology

Citation

Scheibenbogen, C, Freitag, H, Blanco, J, Capelli, E, Lacerda, E, Authier, J, Meeus, M, Castro Marrero, J, Nora-Krukle, Z, Oltra, E, Strand, E B, Shikova, E, Sekulic, S & Murovska, M 2017, 'The European ME/CFS Biomarker Landscape project : An initiative of the European network EUROMENE', Journal of Translational Medicine, vol. 15, no. 1, 162. https://doi.org/10.1186/s12967-017-1263-z