Chemically Pretreated Densification of Juniper Wood for Potential Use in Osteosynthesis Bone Implants

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dc.contributor.authorAndze, Laura
dc.contributor.authorŅefjodovs, Vadims
dc.contributor.authorAndzs, Martins
dc.contributor.authorSkute, Marite
dc.contributor.authorZoldners, Juris
dc.contributor.authorKapickis, Martins
dc.contributor.authorDubnika, Arita
dc.contributor.authorLocs, Janis
dc.contributor.authorVētra, Jānis
dc.contributor.institutionDepartment of Morphology
dc.contributor.institutionInstitute of Anatomy and Anthropology
dc.date.accessioned2025-02-21T09:45:01Z
dc.date.available2025-02-21T09:45:01Z
dc.date.issued2024-10
dc.descriptionPublisher Copyright: © 2024 by the authors.
dc.description.abstractThe aim of the study was to perform treatment of juniper wood to obtain wood material with a density and mechanical properties comparable to bone, thus producing a potential material for use in osteosynthesis bone implants. In the first step, partial delignification of wood sample was obtained by Kraft cooking. The second step was extraction with ethanol, ethanol–water mixture, saline, and water to prevent the release of soluble compounds and increase biocompatibility. In the last step, the thermal densification at 100 °C for 24 h was implemented. The results obtained in the dry state are equivalent to the properties of bone. The swelling of chemically pre-treated densified wood was reduced compared to chemically untreated densified wood. Samples showed no cytotoxicity by in vitro cell assays. The results of the study showed that it is possible to obtain noncytotoxic wood samples with mechanical properties equivalent to bones by partial delignification, extraction, and densification. However, further research is needed to ensure the material’s shape stability, water resistance, and reduced swelling.en
dc.description.statusPeer reviewed
dc.format.extent17
dc.format.extent3910829
dc.identifier.citationAndze, L, Ņefjodovs, V, Andzs, M, Skute, M, Zoldners, J, Kapickis, M, Dubnika, A, Locs, J & Vētra, J 2024, 'Chemically Pretreated Densification of Juniper Wood for Potential Use in Osteosynthesis Bone Implants', Journal of Functional Biomaterials, vol. 15, no. 10, 287. https://doi.org/10.3390/jfb15100287
dc.identifier.doi10.3390/jfb15100287
dc.identifier.issn2079-4983
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/17104
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85207279743&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofJournal of Functional Biomaterials
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectchemical pretreatment
dc.subjectcompressed solid wood
dc.subjectin vitro
dc.subjectjuniper wood
dc.subjectkraft cooking
dc.subjectpartial delignification
dc.subjectwood bone implants
dc.subjectwood densification
dc.subject3.1 Basic medicine
dc.subject2.5 Materials engineering
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectBiomaterials
dc.subjectBiomedical Engineering
dc.titleChemically Pretreated Densification of Juniper Wood for Potential Use in Osteosynthesis Bone Implantsen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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