Serum and urinary calcium level in Latvian patients with sarcoidosis

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dc.contributor.authorRuža, Ieva
dc.contributor.authorLucāne, Zane
dc.date.accessioned2022-08-16T21:03:30Z
dc.date.available2022-08-16T21:03:30Z
dc.date.issued2018
dc.descriptionPublisher Copyright: Copyright © 2018 Termedia Publishing House Ltd. All rights reserved..
dc.description.abstractObjectives: Sarcoidosis is a multisystem granulomatous disease of unknown etiology that in 90% of cases affects the lungs. Calcium metabolism testing can be useful in diagnostics. The aim of the study was to assess the correlation between calcium metabolism and sarcoidosis form of manifestation/demographic indicators. Material and methods: In a retrospective study medical records of all patients (n = 699) who had been hospitalized with suspected sarcoidosis in a specialized clinic of Riga Eastern Clinical University Hospital during the period from January 1 st , 2013 until December 31 st , 2014 were analyzed. Further analysis included only patients with histologically and/or clinically confirmed sarcoidosis (n = 281). Results: Patients' average age at the time of diagnosis was 39 ±13 years. Elevated serum calcium was observed in 9.9% of cases. A statistically significant correlation was found between serum calcium and age (p < 0.01). There was an association between serum calcium and gender (p < 0.05) - levels were higher in men (2.43 mmol/l) than in women (2.40 mmol/l). Elevated calcium in 24-hour urine was observed in 22.7% of patients. The mean value was 232.3 mg/24 h, levels were higher in men (258.7 mg/24 h) than in women (202.3 mg/24 h), and the association with gender was statistically significant (p < 0.01). Conclusions: We can conclude that in Latvia sarcoidosis affects mostly young and middle-aged people. Both serum calcium and calcium in 24-hour urine are important parameters for sarcoidosis diagnostics. Hypercalcemia was found in 9.9% of patients, hypercalciuria in 22.7% of patients, and both were statistically significantly higher in men, regardless of age.en
dc.description.statusPeer reviewed
dc.format.extent5
dc.format.extent72676
dc.identifier.citationRuža, I & Lucāne, Z 2018, 'Serum and urinary calcium level in Latvian patients with sarcoidosis', Reumatologia, vol. 56, no. 6, pp. 377-381. https://doi.org/10.5114/reum.2018.80715
dc.identifier.doi10.5114/reum.2018.80715
dc.identifier.issn0034-6233
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/9433
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85059556616&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofReumatologia
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectHypercalcemia
dc.subjectSarcoidosis
dc.subjectSerum calcium level
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectRheumatology
dc.titleSerum and urinary calcium level in Latvian patients with sarcoidosisen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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