Starproku arteriālā asinsspiediena starpība kā KVS riska marķieris
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Date
2021
Authors
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Journal ISSN
Volume Title
Publisher
Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Pētījums veikts, lai izpētītu savstarpējo saistību starp arteriālā asinsspiediena bilaterālu mērījumu starpību, kardiovaskulāro slimību (KVS) riska faktoriem un absolūto fatālas KVS risku tuvāko 10 gadu laikā.
Pētījuma mērķis bija novērtēt starproku arteriālā asinsspiediena starpību kā potenciālu KVS riska marķieri, kā arī novērtēt starproku arteriālā asinsspiediena starpības saistību ar KVS riska faktoriem.
Šķērsgriezuma pētījums, kas veikts Paula Stradiņa Klīniskās universitātes slimnīcas 24. Asinsvadu ķirurģijas nodaļā laika posmā no 2020. gada novembra līdz 2021. gada februārim. Tika iekļauti 49 pacienti, kuriem tika veikti trīs arteriālā asinsspiediena mērījumi uz katras rokas, tika ievākti dati par pacientu KVS riska faktoriem, pēc SCORE (Systematic COronary Risk Evaluation) sistēmas tika aprēķināts pacientu individuālais KVS procentuālais risks un mērķa procentuālais risks. Par nozīmīgu starproku arteriālā asinsspiediena starpību tika uzskatīts ≥ 10 mmHg.
Pētījuma rezultāti parādīja, ka, salīdzinot pacientu grupas, tika novērota statistiski nozīmīga atšķirība gan pēc SCORE sistēmas aprēķinātajos KVS procentuālā riska rādītājos (p = 0,024), gan pēc aprēķinātā KVS riska līmeņa (p = 0,031). Pētot atsevišķu KVS riska faktoru saistību ar starproku arteriālā asinsspiediena starpību, tika novērota statisiski nozīmīga atšķirība zema blīvuma lipoproteīnu (ZBL) holesterīna (p = 0,018) un triglicerīdu (p = 0,035) līmeņu rādītājos starp pacientu grupām.
Balstoties uz pētījuma rezultātiem, starproku arteriālā asinsspiediena starpības mērījums potenciāli var kalpot kā viegli pieejams un vienkārši pielietojams līdzeklis KVS riska prognozēšanai klīniskajā vidē.
This study is devoted to investigate relationship between difference in bilateral blood pressure recordings, cardiovascular disease (CVD) risk factors and the total 10 year risk for fatal CVD. The aim of this study was to evaluate interarm blood pressure difference as a potential CVD marker, and also evaluate relationship between interarm blood pressure difference and CVD risk factors. This was a cross-sectional study that took place in Pauls Stradiņš Clinical University Hospital’s Department of Vascular Surgery between November, 2020 and February, 2021. A total of 49 patients were enrolled in this study. Blood pressure was measured in both arms 3 times. Patients also were interviewed about their CVD risk factors and underwent assessment of their total 10 year risk for fatal CVD and their target CVD risk using SCORE (Systematic COronary Risk Evaluation) risk calculator. Interarm blood pressure difference ≥ 10 mmHg was considered to be significant. Results of the study showed statistically significant difference of measured total 10 year risk for fatal CVD between patient groups comparing risk assessed in percentages (p = 0,024) and in risk categories (p = 0,031). Evaluating differences of CVD risk factors the results showed statistically significant difference of low-density lipoprotein (LDL) cholesterol (p = 0,018) and triglyceride (p = 0,035) levels between patient groups. Based on results of the study, measurements of interarm blood pressure difference may serve as easily accessible and usable tool for predicting CVD risk in clinical settings.
This study is devoted to investigate relationship between difference in bilateral blood pressure recordings, cardiovascular disease (CVD) risk factors and the total 10 year risk for fatal CVD. The aim of this study was to evaluate interarm blood pressure difference as a potential CVD marker, and also evaluate relationship between interarm blood pressure difference and CVD risk factors. This was a cross-sectional study that took place in Pauls Stradiņš Clinical University Hospital’s Department of Vascular Surgery between November, 2020 and February, 2021. A total of 49 patients were enrolled in this study. Blood pressure was measured in both arms 3 times. Patients also were interviewed about their CVD risk factors and underwent assessment of their total 10 year risk for fatal CVD and their target CVD risk using SCORE (Systematic COronary Risk Evaluation) risk calculator. Interarm blood pressure difference ≥ 10 mmHg was considered to be significant. Results of the study showed statistically significant difference of measured total 10 year risk for fatal CVD between patient groups comparing risk assessed in percentages (p = 0,024) and in risk categories (p = 0,031). Evaluating differences of CVD risk factors the results showed statistically significant difference of low-density lipoprotein (LDL) cholesterol (p = 0,018) and triglyceride (p = 0,035) levels between patient groups. Based on results of the study, measurements of interarm blood pressure difference may serve as easily accessible and usable tool for predicting CVD risk in clinical settings.
Description
Medicīna
Medicine
Veselības aprūpe
Health Care
Medicine
Veselības aprūpe
Health Care
Keywords
hipertensija, starprroku arteriālais asinsspiediens, kardiovaskulārais risks, hypertension, interarm blood pressure difference, cardiovascular risk