The Role of a Ketogenic Diet in Cancer Treatment
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Date
2020
Authors
Journal Title
Journal ISSN
Volume Title
Publisher
Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Šajā literatūras pārskatā tiks novērtēta ketogēnas diētas loma klasiskajā vēža ārstēšanā. Šī pārskata uzdevumi bija aprakstīt vēža izcelsmi dažādiem ģenētisko un vielmaiņas izmaiņu komponentiem un izskaidrot šo izmaiņu rezultātā iegūtās īpašības. Lai aprakstītu klasisko enerģijas metabolismu normālās šūnās, salīdziniet to ar enerģijas metabolismu audzēja šūnās un norādiet uz glikolīzes nozīmi šajā procesā. Papildus analizēt ketogēnas diētas ietekmi uz vēža šūnu enerģijas metabolismu un visbeidzot pārrunāt ketogēnas diētas iespējamo klīnisko nozīmi nākotnē pretvēža terapijā.
In this literature review it will be evaluated the role of a ketogenic diet in the classic treatment of cancer. The tasks of this review was to describe the origin of cancer on different components of genetic and metabolic changes and explain properties gained by these changes. To describe classic energy metabolism in normal cells, compare it to the energy metabolism in tumour cells and point out the importance of glycolysis in this process. Additionally to analyse the effect of a ketogenic diet on the energy metabolism of cancer cells and lastly, to discuss possible clinical significance of a ketogenic diet in the future for anticancer therapy.
In this literature review it will be evaluated the role of a ketogenic diet in the classic treatment of cancer. The tasks of this review was to describe the origin of cancer on different components of genetic and metabolic changes and explain properties gained by these changes. To describe classic energy metabolism in normal cells, compare it to the energy metabolism in tumour cells and point out the importance of glycolysis in this process. Additionally to analyse the effect of a ketogenic diet on the energy metabolism of cancer cells and lastly, to discuss possible clinical significance of a ketogenic diet in the future for anticancer therapy.
Description
Medicīna
Medicine
Veselības aprūpe
Health Care
Medicine
Veselības aprūpe
Health Care
Keywords
“ketogēnā diēta”, “audzēja šūnu metabolsims”, “vēzis kā vielmaiņas slimība”, “adjuvanta vēža terapija”, “kanceroģenēze”, “ketogenic diet”, “tumour cell metabolism”, “cancer as a metabolic disease”, “adjuvant cancer therapy”, “carcinogenesis”