Carotid artery stenting outcomes in high-risk patients receiving best medical therapy : Results from a single high-volume interventional cardiology practice

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dc.contributor.authorTrusinskis, Karlis
dc.contributor.authorVasiljevs, Deniss
dc.contributor.authorKnoka, Evija
dc.contributor.authorSondore, Dace
dc.contributor.authorDombrovskis, Andis
dc.contributor.authorKumsars, Indulis
dc.contributor.authorStrenge, Karlis
dc.contributor.authorBumeistere, Kristine
dc.contributor.authorKareer, Gurjoat S.
dc.contributor.authorErglis, Andrejs
dc.contributor.institutionRīga Stradiņš University
dc.date.accessioned2021-07-15T11:50:01Z
dc.date.available2021-07-15T11:50:01Z
dc.date.issued2016-12-01
dc.descriptionPublisher Copyright: © 2016
dc.description.abstractBackground Carotid artery stenting (CAS) is now being widely used in the treatment of carotid artery stenosis. Recent clinical studies have demonstrated low adverse event rates after CAS. This study evaluates the 30-day and 1-year results in patients treated with CAS and receiving intensive medical therapy in a high-volume percutaneous coronary intervention center. Methods A total of 184 patients underwent CAS between January 2011 and December 2013. In addition to antiplatelet therapy, patients received intensive antihypertensive treatment, high intensity statin and heart rate normalization therapy. Patients were stratified according to age and symptomatic status. Results Most of the patients (86.4%) had at least one high surgical risk criteria. The procedural success rate was 98.4%. The 30-day and 1-year incidence of stroke were 4.1% and 4.5%, respectively. At 30 days the combined rate of stroke/cardiovascular (CV) death/myocardial infarction (MI) was 5.8% and 10.9% in 1 year. The 30-day incidence of stroke/CV death in asymptomatic and symptomatic patients was 5.4% and 4.2%, respectively. Age ≥80 years increased the risk of stroke/CV death/MI at 1 year (OR 4.41; 95% CI 1.06–18.36; P = 0.04). Conclusions The study demonstrated acceptable clinical outcome results in patients with high medical comorbidities treated with CAS and intensive medical therapy. Adverse event rate in symptomatic patients did not exceed the guideline recommended range while in asymptomatic patients it was increased.en
dc.description.statusPeer reviewed
dc.format.extent181433
dc.identifier.citationTrusinskis, K, Vasiljevs, D, Knoka, E, Sondore, D, Dombrovskis, A, Kumsars, I, Strenge, K, Bumeistere, K, Kareer, G S & Erglis, A 2016, 'Carotid artery stenting outcomes in high-risk patients receiving best medical therapy : Results from a single high-volume interventional cardiology practice', Cor et Vasa, vol. 58, no. 6, pp. e569-e575. https://doi.org/10.1016/j.crvasa.2015.09.005
dc.identifier.doi10.1016/j.crvasa.2015.09.005
dc.identifier.issn0010-8650
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/5890
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=84999277855&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofCor et Vasa
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCarotid artery disease
dc.subjectCarotid artery stenosis
dc.subjectCarotid artery stenting
dc.subjectStroke
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectCardiology and Cardiovascular Medicine
dc.titleCarotid artery stenting outcomes in high-risk patients receiving best medical therapy : Results from a single high-volume interventional cardiology practiceen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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