Bone Grafts in Trauma and Orthopaedics

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dc.contributor.authorArchunan, Maheswaran W
dc.contributor.authorPetronis, Sandris
dc.contributor.institutionRīga Stradiņš University
dc.date.accessioned2022-02-22T10:10:02Z
dc.date.available2022-02-22T10:10:02Z
dc.date.issued2021-09-04
dc.description.abstractWorldwide, there are millions of patients each year suffering from bone-related illness due to trauma, degenerative diseases, infections or oncology that require orthopaedic intervention involving bone grafts. This literature review aims to analyse the characteristics of the different bone grafts: autografts, allografts and synthetic bone substitutes. The review will assess their medical value based on their effectiveness as well as scrutinising any drawbacks. The goal is to identify which options can give the optimal result for a patient being treated for a bone defect. Bone autografts remainthe gold standard since there are no issues with histocompatibility or disease transmission while possessing the ideal characteristics: osteogenicity, osteoconductivity and osteoinductivity. However, synthetic options such as calcium phosphate ceramics are becoming popular as a viable alternative for treatment since they can be produced in desired quantitates and yield excellent results while not having the problem of donor site morbidity as seen with autografts. Furthermore, advancements in fields such as bone tissue engineering and three-dimensional printing are generating promising results and could provide a path for excellent treatment in the future. The emergence of such innovations highlights the importance and the constant need for improvement in bone grafting.en
dc.description.statusPeer reviewed
dc.format.extent5
dc.format.extent110419
dc.identifier.citationArchunan, M W & Petronis, S 2021, 'Bone Grafts in Trauma and Orthopaedics', Cureus, vol. 13, no. 9, e17705. https://doi.org/10.7759/cureus.17705
dc.identifier.doi10.7759/cureus.17705
dc.identifier.issn2168-8184
dc.identifier.otherunpaywall: 10.7759/cureus.17705
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/7630
dc.identifier.urlhttps://www.webofscience.com/wos/alldb/full-record/MEDLINE:34650879
dc.language.isoeng
dc.relation.ispartofCureus
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectbone grafts
dc.subjectorthopedics and trauma
dc.subjectbone reconstruction
dc.subjectbone tissue engineering
dc.subjectbone injury
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleBone Grafts in Trauma and Orthopaedicsen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/systematicreview

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