Change in obsessive beliefs as predictor and mediator of symptom change during treatment of obsessive-compulsive disorder - a process-outcome study

Abstract

Background: Cognitive models of obsessive-compulsive disorder suggest that changes in obsessive beliefs are a key mechanism of treatments for obsessive-compulsive disorder. Thus, in the present process-outcome study, we tested whether changes in obsessive beliefs during a primarily cognitive behavioral inpatient treatment predicted treatment outcome and whether these changes mediated symptom changes over the course of treatment. Methods: Seventy-one consecutively admitted inpatients with obsessive-compulsive disorder were assessed with the Yale-Brown Obsessive-Compulsive Scale and the Obsessive Beliefs Questionnaire at treatment intake, after six weeks of treatment and at discharge, and with the Beck-Depression-Inventory-II at intake and discharge. Results: Changes in obsessive beliefs during the first six weeks of treatment predicted obsessive-compulsive symptoms at discharge when controlling for obsessive-compulsive and depressive symptoms at intake in a hierarchical regression analysis. Multilevel mediation analyses showed that reductions in obsessive beliefs partially mediated improvements in obsessive-compulsive symptoms over time. Conclusions: Our findings indicate that decreasing obsessive beliefs in inpatient cognitive behavioral therapy for obsessive-compulsive disorder might be a promising treatment approach.

Description

Publisher Copyright: © 2016 The Author(s).

Keywords

Change mechanism, Cognitive behavioral therapy, Inpatient treatment, Mediator, Obsessive beliefs, Obsessive-compulsive disorder, 5.1 Psychology, 3.2 Clinical medicine, 1.1. Scientific article indexed in Web of Science and/or Scopus database, Psychiatry and Mental health, SDG 3 - Good Health and Well-being

Citation

Diedrich, A, Sckopke, P, Schwartz, C, Schlegl, S, Osen, B, Stierle, C & Voderholzer, U 2016, 'Change in obsessive beliefs as predictor and mediator of symptom change during treatment of obsessive-compulsive disorder - a process-outcome study', BMC Psychiatry, vol. 16, no. 1, 220. https://doi.org/10.1186/s12888-016-0914-6