Early lifestyle interventions in people with impaired glucose tolerance in northern Colombia : The DEMOJUAN project

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dc.contributor.authorBarengo, Noël C.
dc.contributor.authorAcosta, Tania
dc.contributor.authorArrieta, Astrid
dc.contributor.authorRicaurte, Carlos
dc.contributor.authorSmits, Dins
dc.contributor.authorFlorez, Karen
dc.contributor.authorTuomilehto, Jaakko O.
dc.contributor.institutionFaculty of Medicine
dc.date.accessioned2021-06-07T11:25:01Z
dc.date.available2021-06-07T11:25:01Z
dc.date.issued2019-04-02
dc.descriptionPublisher Copyright: © 2019 by the authors.
dc.description.abstractBackground: The objective of the demonstration project for type 2 diabetes prevention in the Barranquilla and Juan Mina (DEMOJUAN) study was to investigate the extent to which it is possible to reach normal glucose metabolism with early lifestyle interventions in people at high risk of type 2 diabetes (prediabetes), compared with those who receive standard usual care. Methods: DEMOJUAN was a randomized controlled trial conducted in Juan Mina and Barranquilla, Northern Colombia. Eligible participants were randomized into one of three groups (control group, initial nutritional intervention, and initial physical activity intervention). The duration of the intervention was 24 months. The main study outcome in the present analysis was reversion to normoglycemia. Relative risks and their corresponding 95% confidence intervals were calculated for reversal to normoglycemia and T2D incidence. Results: There was no statistically significant association between the intervention groups and reversion to normoglycemia. The relative risk of reversion to normoglycemia was 0.88 (95% CI 0.70-1.12) for the initial nutritional intervention group participants and 0.95 (95% CI 0.75-1.20) for the initial physical activity intervention group participants. Conclusions: Our study did not find any statistically significant differences in reversion to normoglycemia or the development of type 2 diabetes between the intervention groups and the control group in this population.en
dc.description.statusPeer reviewed
dc.format.extent854191
dc.identifier.citationBarengo, N C, Acosta, T, Arrieta, A, Ricaurte, C, Smits, D, Florez, K & Tuomilehto, J O 2019, 'Early lifestyle interventions in people with impaired glucose tolerance in northern Colombia : The DEMOJUAN project', International Journal of Environmental Research and Public Health, vol. 16, no. 8, 1403. https://doi.org/10.3390/ijerph16081403
dc.identifier.doi10.3390/ijerph16081403
dc.identifier.issn1661-7827
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/4745
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85065063404&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofInternational Journal of Environmental Research and Public Health
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectField trial
dc.subjectGlucose metabolism disorders
dc.subjectPopulation
dc.subjectPrimary prevention
dc.subjectSouth america
dc.subject3.3 Health sciences
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectPublic Health, Environmental and Occupational Health
dc.subjectHealth, Toxicology and Mutagenesis
dc.subjectSDG 3 - Good Health and Well-being
dc.titleEarly lifestyle interventions in people with impaired glucose tolerance in northern Colombia : The DEMOJUAN projecten
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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