Early Atherosclerosis Registry – Low Density Lipoprotein Cholesterol Level in Patients with Acute Coronary Syndrome and Stable Coronary Artery Disease: a Pilot Study
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Date
2022
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Rīgas Stradiņa universitāte
Rīga Stradiņš University
Rīga Stradiņš University
Abstract
Šī pētījuma mērķis bija noteikt agrīnas aterosklerozes izplatību pacientiem, kuriem tiek veikta koronārā angiogrāfija un/vai perkutānā koronārā intervence, un noteikt zema blīvuma lipoproteīnu holesterīna līmeņa saistību ar hospitalizācijas iemeslu. Agrīna ateoskleroze tika definēta kā vismas vienas koronārās artērijas stenose ≥50% vīriešiem no 18 līdz 55 gadiem un sievietēm no 18 līdz 65 gadiem.
Trīs mēnešu laikā tika veiktas 1430 procedūras, no kurām 15,73% atbilda agrīnas ateosklerozes definīcijai. No visiem agrīnas ateosklerozes pacientiem 21,6% tika stacionēti slimnīcā akūta koronārā sindroma dēļ, un 78,4% no agrīnas ateosklerozes pacientiem tika veiktas plānveida procedūras. Tiem agrīnas ateosklerozes pacientiem, kuri tika hospitalizēti akūta koronārā sindroma dēļ, bija augstāks zema blīvuma lipoproteīnu holesterīna līmenis, salīdzinot ar plānveida koronārā angiogrāfija un perkutānā koronārā intervence grupu. Netika novērotas atšķirības zema blīvuma lipoproteīnu holesterīnu līmeņos starp sievietēm un vīriešiem.
This study aimed to determine the prevalence of early atherosclerosis among patients undergoing conventional coronary angiography and/or percutaneous coronary intervention and to determine the association of low-density lipoprotein cholesterol levels with the cause of hospitalization. Early atherosclerosis was defined as at least one coronary artery stenosis ≥50% in men 18-55 years and women 18-65 years. Over 3 months 1430 procedures were performed of which 15.73% met the definition for early atherosclerosis. Of all early atherosclerosis patients, 21,6% were admitted to the hospital due to acute coronary syndrome and 78.4% were on elective procedures. Those early atherosclerosis patients who were hospitalized because of acute coronary syndrome had higher levels of low-density lipoprotein cholesterol compared to elective conventional coronary angiography and percutaneous coronary intervention group. There was no gender difference in low-density lipoprotein cholesterol levels.
This study aimed to determine the prevalence of early atherosclerosis among patients undergoing conventional coronary angiography and/or percutaneous coronary intervention and to determine the association of low-density lipoprotein cholesterol levels with the cause of hospitalization. Early atherosclerosis was defined as at least one coronary artery stenosis ≥50% in men 18-55 years and women 18-65 years. Over 3 months 1430 procedures were performed of which 15.73% met the definition for early atherosclerosis. Of all early atherosclerosis patients, 21,6% were admitted to the hospital due to acute coronary syndrome and 78.4% were on elective procedures. Those early atherosclerosis patients who were hospitalized because of acute coronary syndrome had higher levels of low-density lipoprotein cholesterol compared to elective conventional coronary angiography and percutaneous coronary intervention group. There was no gender difference in low-density lipoprotein cholesterol levels.
Description
Medicīna
Medicine
Veselības aprūpe
Health Care
Medicine
Veselības aprūpe
Health Care
Keywords
Agrīna ateroskleroze, zema-blīvuma lipoproteīna holesterīns, koronāra sirds slimība, Early atherosclerosis, low-density lipoprotein cholesterol, coronary artery disease