Overlaps in the Pathogenesis of Rosacea and Atherosclerosis
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Date
2018-06-01
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Abstract
Rosacea is a chronic inflammatory skin disease characterised by transient or persistent erythema, telangiectasia, papules, and pustules that predominantly involve central regions of the face. Recent studies have shown a possible clinical association between rosacea and cardiovascular diseases (CVDs). Rosacea and atherosclerosis are both known to have alterations in the innate immune system, enhanced oxidative and endoplasmic reticulum stress. The aim of this review is to delve deep into the pathogenesis of rosacea and atherosclerosis to uncover possible pathogenic overlaps between these chronic inflammatory diseases.
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Publisher Copyright: © 2018 Aleksejs Zavorins et al., published by Sciendo.
Keywords
atherosclerosis, endoplasmic reticulum stress, LL-37, oxidative stress, rosacea, Toll-like receptor 2, 3.2 Clinical medicine, 1.1. Scientific article indexed in Web of Science and/or Scopus database, General, SDG 3 - Good Health and Well-being
Citation
Zavorins, A, Voicehovska, J, Ķisis, J & Lejnieks, A 2018, 'Overlaps in the Pathogenesis of Rosacea and Atherosclerosis', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 72, no. 3, pp. 152-159. https://doi.org/10.2478/prolas-2018-0006