Descemet membrane endothelial keratoplasty in pseudophakic bullous keratopathy : Outcomes and evidence-based suggestions

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dc.contributor.authorBorroni, Davide
dc.contributor.authorFerronato, Melanie
dc.contributor.authorOrube, Ineta
dc.contributor.authorErts, Renars
dc.contributor.authorSepetiene, Svetlana
dc.contributor.authorDrucka, Eva
dc.contributor.authorKrumina, Zita
dc.contributor.institutionRīga Stradiņš University
dc.contributor.institutionDepartment of Ophthalmology
dc.contributor.institutionDepartment of Biology and Microbiology
dc.date.accessioned2021-06-30T08:25:02Z
dc.date.available2021-06-30T08:25:02Z
dc.date.issued2018
dc.descriptionPublisher Copyright: © 2018 Tehran University of Medical Sciences. All rights reserved.
dc.description.abstractThe purpose of the study was to determine clinical outcomes of Descemet Membrane Endothelial Keratoplasty (DMEK) in patients with Pseudophakic Bullous Keratopathy (PBK). The study was conducted at a tertiary referral center. This was a retrospective case series. Pseudophakic eyes having undergone DMEK surgery for Pseudophakic Bullous Keratopathy was considered the object of study. The examination implied the analysis of best corrected visual acuity (BCVA or CDVA), endothelial cell density (ECD), intraocular pressure (IOP), intraoperative and postoperative complications and a follow-up in 1, 3, and 6 months. For the purposes of the study, 25 pseudophakic eyes with PBK were examined. One month after the surgery patients reached a BCVA of 0.49±0.08(M±SD), after 3 months - BCVA of 0.65±0.12(M±SD), and a BCVA of 0.78±0.17 (M±SD) in the last follow-up in 6 months after the surgery (P<0,001). The mean ECD after one month was 1661±133 (M±SD) cells/mm2, after 3 months - 1591±124 (M±SD) cells/mm2, and during the last control in 6 months -1579±128 (M±SD) cells/mm2. The graft detachment rate was 12% (3 cases). Hypertension was observed in one eye (4%), necessitating partial air elimination through a corneal wound within the first hours after the surgery. DMEK may give excellent visual results in Pseudophakic eyes without increasing the risk of complications when compared to Descemet Stripping Automated Endothelial Keratoplasty (DSAEK) and Penetrating Keratoplasty (PKP). Anatomic repair after DMEK is associated with improved corneal clarity and BCVA.en
dc.description.statusPeer reviewed
dc.format.extent6
dc.format.extent178604
dc.identifier.citationBorroni, D, Ferronato, M, Orube, I, Erts, R, Sepetiene, S, Drucka, E & Krumina, Z 2018, 'Descemet membrane endothelial keratoplasty in pseudophakic bullous keratopathy : Outcomes and evidence-based suggestions', Acta Medica Iranica, vol. 56, no. 3, pp. 170-175.
dc.identifier.issn0044-6025
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/5730
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85043310700&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofActa Medica Iranica
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCataract
dc.subjectCornea
dc.subjectDescemet membrane endothelial keratoplasty
dc.subjectDescemet stripping automated endothelial keratoplasty
dc.subjectDMEK
dc.subjectDSAEK
dc.subjectPBK
dc.subjectPenetrating keratoplasty
dc.subjectPKP
dc.subjectPseudophakic bullous keratopathy
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral Medicine
dc.titleDescemet membrane endothelial keratoplasty in pseudophakic bullous keratopathy : Outcomes and evidence-based suggestionsen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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