Regional Lung Blood Perfusion Measured with Laser Doppler Method During Body Position Change, Valsalva Manoeuvre and Cardiopulmonary Bypass

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dc.contributor.authorTaivans, Immanuels
dc.contributor.authorStrazda, Gunta
dc.contributor.authorPorīte, Nora
dc.contributor.authorVanags, Indulis
dc.contributor.authorLejnieks, Juris
dc.contributor.authorLācis, Romans
dc.contributor.authorStrīķe, Eva
dc.contributor.institutionDepartment of Anaesthesiology, Intensive Care and Clinical simulations
dc.date.accessioned2021-10-21T08:00:01Z
dc.date.available2021-10-21T08:00:01Z
dc.date.issued2008-01-01
dc.description.abstractMethodological approaches to investigate local regulatory mechanisms of lung blood supply in humans are restricted. We tried a new approach using laser Doppler technique. During bronchoscopy, an angled laser Doppler flow probe was introduced through a biopsy channel and wedged into small bronchus. Laser light penetrated the wall of small bronchus and was reflected from blood cells running through neighbouring capillaries. Regional blood perfusion changes were recorded during body position change from vertical to supine and back to vertical, while performing Valsalva maneuver and during cardiac bypass surgery. Body position change and Valsalva maneuver markedly influenced the blood perfusion signal. During cardiac bypass when lungs were supplied with blood only through bronchial arteries regional blood perfusion dropped substantially on average from 93 ± 42 to 7.3 ± 4.3 perfusion units. We conclude that blood perfusion measured with this method reflect mainly the pulmonary vascular bed and may be used for investigation of its local regulatory mechanisms.en
dc.description.statusPeer reviewed
dc.format.extent6
dc.format.extent272020
dc.identifier.citationTaivans, I, Strazda, G, Porīte, N, Vanags, I, Lejnieks, J, Lācis, R & Strīķe, E 2008, 'Regional Lung Blood Perfusion Measured with Laser Doppler Method During Body Position Change, Valsalva Manoeuvre and Cardiopulmonary Bypass', Proceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences, vol. 62, no. 4/5, pp. 170-175. https://doi.org/10.2478/v10046-008-0026-x
dc.identifier.doi10.2478/v10046-008-0026-x
dc.identifier.issn1407-009X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/6694
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85026037540&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofProceedings of the Latvian Academy of Sciences, Section B: Natural, Exact, and Applied Sciences
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectcardiac bypass
dc.subjectLaser Doppler technique
dc.subjectpulmonary vascular bed
dc.subjectValsalva manoeuvre
dc.subject3.2 Clinical medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.subjectGeneral
dc.titleRegional Lung Blood Perfusion Measured with Laser Doppler Method During Body Position Change, Valsalva Manoeuvre and Cardiopulmonary Bypassen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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