Opportunities of Amlodipine as a Potential Candidate in the Evaluation of Drug Compliance during Antihypertensive Therapy

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dc.contributor.authorKustovs, Dmitrijs
dc.contributor.authorUrtāne, Inga
dc.contributor.authorSevostjanovs, Eduards
dc.contributor.authorMoreino, Eva
dc.contributor.authorTrušinskis, Kārlis
dc.contributor.institutionDepartment of Pharmaceutical Chemistry
dc.contributor.institutionDepartment of Internal Diseases
dc.date.accessioned2023-02-14T10:45:01Z
dc.date.available2023-02-14T10:45:01Z
dc.date.issued2023-02-10
dc.descriptionFunding Information: The present study was part of the doctoral research program. The current doctoral research project was funded by the Riga Stradiņš University (Nr. 6-ZD-22/15/2021). The funder had no role in the design and conduct of the study; the collection, management, analysis, and interpretation of the data; and the preparation, review, or approval of the manuscript. Publisher Copyright: © 2023 by the authors.
dc.description.abstractBackground and Objectives: Blood pressure measurement is essential evidence to establish that the chosen medicine and dosage are appropriate, and also indirectly indicates whether the medicine is being used at all. Therefore, current research compares adherence to the target blood pressure at home and in the hospital between different age groups, using similar combinations of the drugs prescribed by the doctor within ongoing antihypertensive therapy. Moreover, it is very important to develop a method for the determination of amlodipine and its metabolite, which would suitable for clinical applications, when the result is needed as quick as possible. Materials and Methods: This prospective study included patients aged ≥18 years who were diagnosed with hypertension. Subjects were divided into two age groups according to European Society of Cardiology (ESC) hypertension guidelines; older patients (≥65 years) and adult patients (en
dc.description.statusPeer reviewed
dc.format.extent3254518
dc.identifier.citationKustovs, D, Urtāne, I, Sevostjanovs, E, Moreino, E & Trušinskis, K 2023, 'Opportunities of Amlodipine as a Potential Candidate in the Evaluation of Drug Compliance during Antihypertensive Therapy', Medicina, vol. 59 , no. 2, 340. https://doi.org/10.3390/medicina59020340
dc.identifier.doi10.3390/medicina59020340
dc.identifier.issn1010-660X
dc.identifier.urihttps://dspace.rsu.lv/jspui/handle/123456789/10366
dc.identifier.urlhttp://www.scopus.com/inward/record.url?scp=85148902823&partnerID=8YFLogxK
dc.language.isoeng
dc.relation.ispartofMedicina
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectamlodipine
dc.subjectadherence
dc.subjectdrug monitoring
dc.subjectdehydro-amlodipine
dc.subjecthypertension
dc.subject3.2 Clinical medicine
dc.subject3.1 Basic medicine
dc.subject1.1. Scientific article indexed in Web of Science and/or Scopus database
dc.titleOpportunities of Amlodipine as a Potential Candidate in the Evaluation of Drug Compliance during Antihypertensive Therapyen
dc.type/dk/atira/pure/researchoutput/researchoutputtypes/contributiontojournal/article

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