Browsing by Author "Tirane, Mara"

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    Accuracy of 68Ga-PSMA-11 PET/CT and multiparametric MRI for the detection of local tumor and lymph node metastases in early biochemical recurrence of prostate cancer
    (2020) Radzina, Maija; Tirane, Mara; Roznere, Lilita; Zemniece, Liene; Dronka, Laura; Kalnina, Marika; Mamis, Edgars; Biederer, Juergen; Lietuvietis, Vilnis; Freimanis, Arvis; Vjaters, Egils; Department of Radiology
    Anatomical and functional imaging plays a decisive role for detection and staging, of prostate cancer both primarily and post-treatment. While multiparametric MRI offers anatomic imaging with excellent soft tissue contrast, hybrid imaging based on positron emission tomography in combination with computed tomography (PET/CT) contributes functional imaging capacities. Since 68Ga-PSMA-11 was expected to be more efficient than the prior Choline-based PET radiotracers, it was the aim of the study to evaluate the diagnostic performance of the 68Ga-PSMA-11 PET/CT and multiparametric MRI in patients with recurrent prostate cancer and low PSA levels. 32 out of a cohort of 128 prostate cancer patients with biochemical relapse were referred for 68Ga-PSMA-11 PET/CT, MRI and bone scintigraphy. According to the histopathologically or clinically defined reference standard all results were classified as true positive, false positive, true negative or false negative. Local recurrence was present in 11/32 patients, lymph node metastases - in 13/32 patients and, bone metastases - in 6/32 patients. Against the standard of reference, sensitivity, specificity and accuracy for local recurrence of PET/CT were 63.6 %; 73.7%; 77.8%, respectively. MRI reached 90.9%; 94.7%; 92.3%, respectively. For local lymph node metastases PET/CT - 83.3%; 80.0% and 90.6%, respectively. MRI - 41.7%; 94.4%; 72.0%, respectively. For evaluation of bone metastases in PET/CT - 83.3%; 92.0%; 71.0%, respectively. Bone scintigraphy - 50.0%; 84.0%; 77.4%, respectively. In conclusion, mpMRI offered the better diagnostic accuracy in the detection of local recurrence and while PSMA PET/CT was superior in the detection of distant and lymph node metastases.
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    Latvian experience in conservative management of abnormally invasive placenta : two case reports
    (2019) Bokucava, Diana; Vitina, Sandra; Jansone, Maira; Tirane, Mara; Krastina, Zane; Prostaka, Kristine; Vedmedovska, Natālija; Rīga Stradiņš University
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    Multislice Computed Tomography Imaging of Diverticultis Complication: Colovenous Fistula
    (2010-01-01) Radzina, Maija; Laganovskis, Andris; Tirane, Mara; Zvaigzne, Ligita; Prieditis, Peteris; Bruns, Voldemars; Lugovska, Svetlana
    Acute colon pathology as diverticulitis is a frequent and important gastrointestinal disease, but the clinical diagnosis is often difficult to state. Several radiological studies have been used to assist in the diagnosis of acute diverticulitis (e.g. barium enema, ultrasound, and computed tomography (CT). Colovenous fistula is a rare complication of diverticulitis. We have analyzed MSCT imaging role in evaluation of such complicated form of diverticular disease.