Browsing by Author "Teraudkalna, Madara"

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    Ebstein anomaly and right aortic arch in patient with Charge syndrome
    (2021-11-13) Lubaua, Ingūna; Teraudkalna, Madara; Department of Paediatrics
    Ebstein anomaly is a rare congenital heart disease characterized by a varying degree of anatomical and functional abnormalities of tricuspid valve and right ventricle. It often coexists with other congenital cardiac malformations. Up to 79–89% of patients with Ebstein anomaly have interatrial communication in the form of patent oval foramen or atrial septal defect and more than one-third has other types of cardiac malformations. Association between Ebstein anomaly and right aortic arch is extremely rare and only few cases have been described in the literature so far. Much rarer than with other cardiac malformations, Ebstein anomaly is associated with non-cardiac malformations or genetic syndromes. Several cases of association between Ebstein anomaly and Charge syndrome have been reported, nevertheless, Ebstein anomaly accounts for less than 1% of cardiac defects seen in patients with Charge syndrome. In this case report, we present a unique case of a patient with Charge syndrome where both Ebstein anomaly and right aortic arch are present. The diagnosis of Ebstein anomaly and right aortic arch was established prenatally. In the first years of life, the patient did not exhibit any remarkable symptoms. However, over time, deterioration of right ventricle function and increased tricuspid regurgitation were observed, requiring consideration of surgical treatment at the age of five. In addition, delay in physical, motor, and mental development was observed and thus, at the age of five, the patient was consulted by a medical geneticist and a gene panel to test for structural heart defects was ordered. The test showed a mutation in chromodomain helicase DNA binding protein 7 (CHD7) gene, which, along with clinical features, allowed to establish a diagnosis of Charge syndrome. To the best of the authors’ knowledge, this is the first case report of a patient with Charge syndrome, Ebstein anomaly, and right aortic arch that has been described in the literature.
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    Knowledge, Attitudes and COVID-19-related Behavior among Individuals Aged 50 and Older in Latvia
    (2021) Gehtmane-Hofmane, Ilona; Teraudkalna, Madara; Rajevska, Olga; Koroleva, Ilze; Reine, Ieva; Lubkina, Velta; Laganovska, Karīna; Kaupužs, Aivars; Rīga Stradiņš University
    The coronavirus disease 2019 (COVID-19) was declared a pandemic by the WHO on March11,2020,due to its high infection rate,which caused thousands of deaths worldwide and expanding.The evolving outbreak of COVID-19 requireshealth-protective behavior that can alleviate the severity of an epidemic. Therefore, recognizing the underlying drivers of health-protective behavior against COVID-19 is urgently needed to form policy responses. The purpose of this study was to investigate the individual-level underlying drivers affecting the formation of knowledge, attitudes, and COVID-19-related health-protective behavior among individuals aged 50 and older who are more vulnerable to complications of infection because of their age.The factors making individuals more vulnerable are also associated with the ability to access and understand information, make well-informed decisions, and take health-protective and promoting actions,especially when information itself is not timely, trusted, consistent, or actionable. The researchers used data from a representative population sample consisting of 50-80-year-old individuals, obtained from in-depth, semi-structuredtelephone interviews during July –August2020,between the first and second waves of COVID-19. For conducting qualitative data analyses, the Grounded Theory (GT) approach for developing code structure was used.