Browsing by Author "Staka, Aiga"

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    Impact of oat-based products on human gastrointestinal tract
    (2015-09-01) Staka, Aiga; Bodnieks, Edgars; Pukitis, Aldis; Faculty of Medicine
    Oat is rich in valuable nutrients. In comparison to other cereals, oat contains more total proteins, carbohydrate, fat, non-starch fibre, as well as unique antioxidants (one of them - avenanthramides), vitamins, and minerals. One of the most often studied components of oats is β-glucan - a type of soluble dietary fibre located throughout the starch endosperm, but with highest concentration in the bran. Many studies have shown the beneficial health effects of oat β-glucan as a soluble dietary fibre. Until now, most of the studies on this nutrient have been conducted in the cardiovascular and diabetology field. This article aimed to review the literature on studies that investigated the effects of oat-based products on human gastrointestinal tract - gastrointestinal microflora, irritable bowel syndrome, inflammatory bowel disease as well as prevention/treatment of colorectal cancer. A literature search was conducted using PubMed database. More than 80 potential articles were identified, which were selected afterwards according to aims of our study. Studies done on human were preferred. A long-term dietary intake of oat-based products improves human intestinal microflora, could have benefits in irritable bowel syndrome, and probable effects were seen in patients with ulcerative colitis, but this remains to be proven. There are few studies regarding prevention/treatment of colorectal cancer and they do not show clear benefit nor provide recommendations.
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    McKittrick-Wheelock Syndrome: A Case Report
    (2016) Cernevskis, Harijs; Staka, Aiga; Pukitis, Aldis; Silda, Anna; Kuzema, Viktorija; Mihailova, Inese; Brikuns, Andrejs; Pētersons, Aivars; Faculty of Medicine
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    Successful full-term pregnancy after preterm event in a liver transplant patient : a case report
    (2023-12) Galsone, Ramona; Vītiņa, Sandra; Jansone, Maira; Staka, Aiga; Mohammadian, Reza
    Background: Pregnancy after liver transplantation poses a significant challenge to both the patient and the transplant team. Case presentation: We present the case of a 19-year-old European patient who underwent liver transplantation 5 years previously owing to autoimmune hepatitis. Poor compliance with immunosuppressive therapy and missed follow-up visits during the patient’s first pregnancy likely contributed to her liver function deterioration, hospitalization, and failed pregnancy. Owing to the patient’s complex medical history, combined immunosuppressive treatment, and risks to the fetus, her second pregnancy was high risk. However, close outpatient monitoring and adherence to treatment led to a successful, uneventful, full-term pregnancy and healthy delivery. Conclusion: Liver transplant recipients who desire to become pregnant require careful planning and management to ensure optimal outcomes for both the mother and the fetus. A personalized strategy is necessary to balance the potential benefits of childbirth with the risks involved in pregnancy after liver transplantation.